Nexium and Edecrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Edecrin (ethacrynic acid). Common drug interactions include confusional state among females and asthma among males.

The phase IV clinical study analyzes what interactions people have when they take Nexium and Edecrin. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.

What is Edecrin?

Edecrin has active ingredients of ethacrynic acid. It is often used in fluid retention. eHealthMe is studying from 252 Edecrin users. Check the latest studies of Edecrin.



On Jul, 18, 2026

18 people who take Nexium and Edecrin together, and have interactions are studied.

Nexium and Edecrin drug interactions.

What are the common drug interactions of Nexium and Edecrin, by gender? *:

female:

  1. Confusional state
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Depression
  4. Fall
  5. Generalised oedema (swelling all over the body)
  6. Hip fracture
  7. Hyperhidrosis (abnormally increased sweating)
  8. Injury
  9. Lung disorder (lung disease)
  10. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

male:

  1. Asthma
  2. Blood potassium decreased
  3. Incisional hernia (hernia caused by an incompletely-healed surgical wound)
  4. Joint injury
  5. Liver disorder (liver diseases)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Migraine (headache)
  8. Muscle spasms (muscle contraction)
  9. Osteitis deformans (a disease of bone occurring in the middle aged and elderly; excessive bone destruction sometimes leading to bone pain)
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

What are the common drug interactions of Nexium and Edecrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Eosinophilia (eosinophil count in the peripheral blood exceeds)

20-29:

n/a

30-39:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Injury
  3. Pain
  4. Pulmonary embolism (blockage of the main artery of the lung)

40-49:

  1. Cardiac disorder
  2. Cardiac failure
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Diarrhoea
  5. Impaired work ability
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Oedema peripheral (superficial swelling)
  8. Pain
  9. Pericardial effusion (fluid around the heart)
  10. Renal failure (kidney dysfunction)

50-59:

  1. Drug ineffective
  2. Asthma
  3. Blood potassium decreased
  4. Blood pressure inadequately controlled
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cough
  7. Eating disorder
  8. Fall
  9. Gastrointestinal inflammation (inflammation of stomach and intestine)
  10. Headache (pain in head)

60+:

  1. Cataract (clouding of the lens inside the eye)
  2. Neuropathy peripheral (surface nerve damage)
  3. Gait disturbance
  4. Insomnia (sleeplessness)
  5. Asthenia (weakness)
  6. Back pain
  7. Confusional state
  8. Depression
  9. Drug ineffective
  10. Fall

What are the existing conditions these people have? *

  1. High Blood Pressure: 6 people, 33.33%
  2. Oedema (fluid collection in tissue): 4 people, 22.22%
  3. Immune System Disorder: 2 people, 11.11%
  4. Depression: 1 person, 5.56%
  5. Fluid Imbalance (imbalance of fluid in body in intake and fluid lost): 1 person, 5.56%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.56%
  7. Fatigue (feeling of tiredness): 1 person, 5.56%
  8. Dry Skin: 1 person, 5.56%
  9. Drug Hypersensitivity: 1 person, 5.56%
  10. Weakness: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium and Edecrin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nexium and Edecrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Edecrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Edecrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium and ethacrynic acid (the active ingredients of Nexium and Edecrin, respectively), and Nexium and Edecrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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