Nexium and Folacin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Folacin (folic acid). Common drug interactions include abdominal pain among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Nexium and Folacin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.

What is Folacin?

Folacin has active ingredients of folic acid. eHealthMe is studying from 1,350 Folacin users. Check the latest studies of Folacin.

On Jul, 13, 2026

22 people who take Nexium and Folacin together, and have interactions are studied.

What are the common drug interactions of Nexium and Folacin, by gender? *:

female:

Abdominal pain
Anal haemorrhage
Breast cancer
Cushingoid (obesity and weakening of the muscles)
Cytomegalovirus colitis (an inflammation of the colon from virus)
Diarrhoea
Drug exposure during pregnancy
Epistaxis (bleed from the nose)
Haemoglobin decreased
Listeria sepsis (listeria blood infection)

male:

Abdominal pain upper
Bradycardia (abnormally slow heart action)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Parkinson's disease
Poisoning
Renal failure (kidney dysfunction)
Tendon disorder (disease of tendon)
Cerebral atrophy (decrement in size of brain)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Nexium and Folacin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anal haemorrhage
Cushingoid (obesity and weakening of the muscles)
Cytomegalovirus colitis (an inflammation of the colon from virus)
Drug exposure during pregnancy
Epistaxis (bleed from the nose)
Listeria sepsis (listeria blood infection)
Overweight
Rash papular (redness with papule)
Rash pruritic (redness with itching)
Scab (a hard coating on the skin formed during the wound healing)

20-29:

n/a

30-39:

Respiratory tract infection
Tendon disorder (disease of tendon)

40-49:

n/a

50-59:

Haemoglobin decreased
Oedema peripheral (superficial swelling)
Pyrexia (fever)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Retinal artery embolism (a blockage in one of the small arteries that carry blood to the retina)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Extremity necrosis (death of body tissue of arms and legs)
Necrosis (the death of body tissue)

60+:

Breast cancer
Abdominal pain upper
Drug administration error
Dysphagia (a condition in which swallowing is difficult or painful)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Eye haemorrhage (bleeding in the eye)
Gastrointestinal carcinoma (cancer of stomach or intestine)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Gingival bleeding (bleeding gums)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 22.73%
Gastritis (inflammation of stomach): 3 people, 13.64%
Weber-Christian Disease (a recurring inflammation of fatty layers of tissue present beneath the skin): 2 people, 9.09%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 9.09%
Type 2 Diabetes: 2 people, 9.09%
Primary Hypothyroidism (failure of the thyroid gland to produce or release thyroid hormones into the bloodstream): 2 people, 9.09%
Pain: 2 people, 9.09%
Osteoporosis (bones weak and more likely to break): 2 people, 9.09%
Growth Hormone Deficiency: 2 people, 9.09%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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