Nexium and Ingrezza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Ingrezza (valbenazine tosylate). Common drug interactions include staring among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Nexium and Ingrezza. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.

What is Ingrezza?

Ingrezza has active ingredients of valbenazine tosylate. eHealthMe is studying from 23,666 Ingrezza users. Check the latest studies of Ingrezza.



On Jul, 14, 2026

81 people who take Nexium and Ingrezza together, and have interactions are studied.

Nexium and Ingrezza drug interactions.

What are the common drug interactions of Nexium and Ingrezza, by gender? *:

female:

  1. Staring (a prolonged gaze or fixed look)
  2. Suicidal ideation
  3. Visual impairment
  4. Tardive dyskinesia (a disorder that involves involuntary movements)
  5. Drug ineffective
  6. Fall
  7. Fatigue (feeling of tiredness)
  8. Dyskinesia (abnormality or impairment of voluntary movement)
  9. Insomnia (sleeplessness)
  10. Dry mouth

male:

  1. Fatigue (feeling of tiredness)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Increased appetite
  4. Insomnia (sleeplessness)
  5. Loss of consciousness
  6. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  7. Urinary retention (the inability to completely or partially empty the bladder)
  8. Weight increased
  9. Abdominal discomfort
  10. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

What are the common drug interactions of Nexium and Ingrezza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Initial insomnia (feeling of inadequate or poor-quality sleep)
  2. Insomnia (sleeplessness)
  3. Weight increased

30-39:

  1. Dyspnoea (difficult or laboured respiration)
  2. Completed suicide (act of taking one's own life)

40-49:

  1. Confusional state
  2. Drooling (drop saliva uncontrollably from the mouth)
  3. Dyskinesia (abnormality or impairment of voluntary movement)
  4. Hyperhidrosis (abnormally increased sweating)
  5. Depression
  6. Knee arthroplasty
  7. Post procedural infection
  8. Suicidal ideation
  9. Adverse drug reaction

50-59:

  1. Dizziness
  2. Tardive dyskinesia (a disorder that involves involuntary movements)
  3. Emotional disorder
  4. Restlessness (not able to rest)
  5. Abdominal discomfort
  6. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  7. Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
  8. Depressed mood
  9. Depression
  10. Dry mouth

60+:

  1. Fatigue (feeling of tiredness)
  2. Tardive dyskinesia (a disorder that involves involuntary movements)
  3. Aggression
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  6. Dizziness
  7. Dry mouth
  8. Dysarthria (speech disorder)
  9. Increased appetite
  10. Loss of consciousness

What are the existing conditions these people have? *

  1. Tardive Dyskinesia (a disorder that involves involuntary movements): 63 people, 77.78%
  2. Depression: 9 people, 11.11%
  3. Stress And Anxiety: 7 people, 8.64%
  4. Pain: 6 people, 7.41%
  5. Hypersensitivity: 6 people, 7.41%
  6. High Blood Cholesterol: 6 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Nexium and Ingrezza?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nexium and Ingrezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ingrezza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ingrezza and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on esomeprazole magnesium and valbenazine tosylate (the active ingredients of Nexium and Ingrezza, respectively), and Nexium and Ingrezza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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