Nexium and Minirin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Minirin (desmopressin acetate). Common drug interactions include hyponatraemia among females and clostridium difficile colitis among males.
The phase IV clinical study analyzes what interactions people have when they take Nexium and Minirin. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.
What is Minirin?
Minirin has active ingredients of desmopressin acetate. It is often used in diabetes insipidus. eHealthMe is studying from 1,364 Minirin users. Check the latest studies of Minirin.
37 people who take Nexium and Minirin together, and have interactions are studied.

What are the common drug interactions of Nexium and Minirin, by gender? *:
female:
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Fall
- Clear cell carcinoma of the kidney (cancer of clear cell of kidney)
- Furuncle (infection of the hair follicle)
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Balance disorder
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- Neutropenia (an abnormally low number of neutrophils)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Abdominal pain
male:
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Cytomegalovirus enterocolitis (virus infection of intestine and colon)
- Subdural haemorrhage (bleeding between the skull and the surface of the brain)
- Sudden cardiac death
- Metastases to lung (cancer spreads to lung)
- Haematuria (presence of blood in urine)
- Cellulitis (infection under the skin)
- Drug ineffective
- Dyskinesia (abnormality or impairment of voluntary movement)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
What are the common drug interactions of Nexium and Minirin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Furuncle (infection of the hair follicle)
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Bone marrow failure
30-39:
- Drug ineffective
- Dyskinesia (abnormality or impairment of voluntary movement)
- Haematuria (presence of blood in urine)
- Polyuria (production of too much dilute urine)
- Respiratory tract infection
40-49:
- Abdominal pain
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Bleeding time prolonged
- Contusion (a type of hematoma of tissue in which capillaries)
- Infusion site extravasation (flow of (blood or lymph) from infusion site)
- Nausea (feeling of having an urge to vomit)
- Oedema peripheral (superficial swelling)
- Poor peripheral circulation
50-59:
- Neutropenia (an abnormally low number of neutrophils)
60+:
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Pituitary infarction (death of an area of tissue in the pituitary gland)
- Subdural haemorrhage (bleeding between the skull and the surface of the brain)
- Sudden cardiac death
- Cytomegalovirus enterocolitis (virus infection of intestine and colon)
- Metastases to lung (cancer spreads to lung)
- Balance disorder
- Fall
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
What are the existing conditions these people have? *
- Stress And Anxiety: 9 people, 24.32%
- Depression: 8 people, 21.62%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 18.92%
- Micturition Urgency (urgency to pass the urine): 5 people, 13.51%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 10.81%
- Neuralgia (pain in one or more nerves): 3 people, 8.11%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 3 people, 8.11%
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 8.11%
- Hyperkalemia (damage to or disease of the kidney): 3 people, 8.11%
- Furuncle (infection of the hair follicle): 3 people, 8.11%
* Approximation only. Some reports may have incomplete information.
Do you take Nexium and Minirin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nexium and Minirin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Minirin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nexium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Minirin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium and desmopressin acetate (the active ingredients of Nexium and Minirin, respectively), and Nexium and Minirin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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