Nexium and Prasugrel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Prasugrel (prasugrel). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Nexium and Prasugrel. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,677 Nexium users. Check the latest studies of Nexium.
What is Prasugrel?
Prasugrel has active ingredients of prasugrel. eHealthMe is studying from 1,193 Prasugrel users. Check the latest studies of Prasugrel.
28 people who take Nexium and Prasugrel together, and have interactions are studied.

What are the common drug interactions of Nexium and Prasugrel, by gender? *:
female:
- Chronic kidney disease
- Anaemia (lack of blood)
- Epistaxis (bleed from the nose)
- Haemorrhage subcutaneous (bleeding from skin)
- Pneumonia
- Volvulus (obstruction caused by twisting of the stomach or intestine)
- Cardiac failure
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Renal failure (kidney dysfunction)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Decreased appetite
- Dysgeusia (disorder of the sense of taste)
- Heart rate increased
- Hypertension (high blood pressure)
- Pleural effusion (water on the lungs)
- Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Weight decreased
What are the common drug interactions of Nexium and Prasugrel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Atrioventricular block (heart block)
- Chest pain
- Flushing (the warm, red condition of human skin)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Weight increased
50-59:
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Renal impairment (severely reduced kidney function)
- Breast cancer
- Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Depression
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Abdominal discomfort
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Decreased appetite
- Dysgeusia (disorder of the sense of taste)
- Fatigue (feeling of tiredness)
- Heart rate increased
- Hypertension (high blood pressure)
What are the existing conditions these people have? *
- Stable Angina (a constant chest pain): 7 people, 25.00%
- Acute Myocardial Infarction (acute heart attack): 6 people, 21.43%
- Nausea (feeling of having an urge to vomit): 4 people, 14.29%
- Diabetes: 4 people, 14.29%
- Heart Attack: 4 people, 14.29%
- High Blood Cholesterol: 4 people, 14.29%
- High Blood Pressure: 3 people, 10.71%
- Angina Unstable (chest pain due to ischemia of the heart muscle- unstable): 2 people, 7.14%
- Cardiac Disorder: 2 people, 7.14%
- Chest Pain: 2 people, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Nexium and Prasugrel?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nexium and Prasugrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Prasugrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nexium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prasugrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium and prasugrel (the active ingredients of Nexium and Prasugrel, respectively), and Nexium and Prasugrel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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