Nexium and Ticlid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nexium (esomeprazole magnesium) and Ticlid (ticlopidine hydrochloride). Common drug interactions include weight decreased among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Nexium and Ticlid. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Nexium?
Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.
What is Ticlid?
Ticlid has active ingredients of ticlopidine hydrochloride. eHealthMe is studying from 3,094 Ticlid users. Check the latest studies of Ticlid.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
34 people who take Nexium and Ticlid together, and have interactions are studied.

What are the common drug interactions of Nexium and Ticlid, by gender? *:
female:
- Weight decreased
- Anaemia (lack of blood)
- Anaphylactic reaction (serious allergic reaction)
- Asthenia (weakness)
- Back pain
- Confusional state
- Cough
- Dysarthria (speech disorder)
- Dysstasia (difficulty in standing)
- Erythema (redness of the skin)
male:
- Chronic kidney disease
- Renal failure acute (rapid kidney dysfunction)
- Diabetes mellitus inadequate control
- Diarrhoea
- Emotional distress
- Fatigue (feeling of tiredness)
- Hyperhidrosis (abnormally increased sweating)
- Hypokalaemia (low potassium)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Occult blood positive
What are the common drug interactions of Nexium and Ticlid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Loss of libido (loss of sexual urge)
- Anaphylactic reaction (serious allergic reaction)
- Rash
60+:
- Chronic kidney disease
- Renal failure acute (rapid kidney dysfunction)
- Cardiogenic shock (inadequate circulation of blood)
- Cardiomegaly (increased size of heart than normal)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Diabetes mellitus inadequate control
- Emotional distress
- Hyperhidrosis (abnormally increased sweating)
- Hypokalaemia (low potassium)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
What are the existing conditions these people have? *
- High Blood Pressure: 9 people, 26.47%
- Pain: 8 people, 23.53%
- High Blood Cholesterol: 7 people, 20.59%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 17.65%
- Thrombosis (formation of a blood clot inside a blood vessel): 5 people, 14.71%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 11.76%
- Malaria (a parasitic disease due to mosquito bite): 4 people, 11.76%
- Asthma: 4 people, 11.76%
- Bacterial Infection: 4 people, 11.76%
- Depression: 4 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Nexium and Ticlid?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Nexium and Ticlid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nexium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ticlid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nexium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ticlid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Dr. Anthony Wong, "Esomeprazole and gynaecomastia in obese adults", WHO pharmaceuticals newsletter: 2019, No. 2, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on esomeprazole magnesium and ticlopidine hydrochloride (the active ingredients of Nexium and Ticlid, respectively), and Nexium and Ticlid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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