Nicotine and Haloperidol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nicotine (nicotine) and Haloperidol (haloperidol). Common drug interactions include vasospasm among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Nicotine and Haloperidol. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Haloperidol?

Haloperidol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 16,637 Haloperidol users. Check the latest studies of Haloperidol.

On Jun, 12, 2026

99 people who take Nicotine and Haloperidol together, and have interactions are studied.

Nicotine and Haloperidol drug interactions.

What are the common drug interactions of Nicotine and Haloperidol, by gender? *:

female:

Vasospasm (sudden constriction of a blood vessel, reducing its diameter and flow rate)
Cardiac enzymes increased
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Type 2 diabetes mellitus
Abdominal pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Hypertension (high blood pressure)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug ineffective

male:

Pyrexia (fever)
Hypoxia (low oxygen in tissues)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Abdominal pain
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Death
Disease progression

What are the common drug interactions of Nicotine and Haloperidol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hyperprolactinaemia (abnormally high levels of prolactin in the blood)

20-29:

Head injury
Aggression
Agitation (state of anxiety or nervous excitement)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pain
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Suicidal ideation
Abdominal pain
Abnormal behaviour
Anger

30-39:

Depression
Abdominal pain
Abdominal pain lower
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Blood creatine phosphokinase increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cellulitis (infection under the skin)
Chest pain
Cholecystitis acute (rapid infection of gallbladder)
Cough

40-49:

Prinzmetal angina (cardiac chest pain at rest that occurs in cycles)
Chest pain
Nausea (feeling of having an urge to vomit)
Mitral valve incompetence (inefficient heart valve)
Blood pressure decreased
Heart rate decreased
Somnolence (a state of near-sleep, a strong desire for sleep)
Vasospasm (sudden constriction of a blood vessel, reducing its diameter and flow rate)
Cardiac enzymes increased
Neutropenia (an abnormally low number of neutrophils)

50-59:

Acute respiratory failure
Blood magnesium decreased
Blood pressure diastolic increased
Blood pressure increased
Colitis pseudomembranous (antibiotic-associated diarrhoea)
Death
Decreased appetite
Depressed level of consciousness
Electrocardiogram qt corrected interval prolonged
Eosinophil count increased

60+:

Pyrexia (fever)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dysuria (painful or difficult urination)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hypotension (abnormally low blood pressure)
Rash
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Delirium (wild excitement)
Drug ineffective
Rectal haemorrhage (bleeding from anus)

What are the existing conditions these people have? *

Pain: 19 people, 19.19%
High Blood Pressure: 18 people, 18.18%
Agitation (state of anxiety or nervous excitement): 15 people, 15.15%
Stress And Anxiety: 8 people, 8.08%
Constipation: 8 people, 8.08%
Headache (pain in head): 6 people, 6.06%
Depression: 6 people, 6.06%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.05%

* Approximation only. Some reports may have incomplete information.

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