Nicotine and Letairis drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nicotine (nicotine) and Letairis (ambrisentan). Common drug interactions include chest pain among females and abasia among males.

The phase IV clinical study analyzes what interactions people have when they take Nicotine and Letairis. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Letairis?

Letairis has active ingredients of ambrisentan. It is often used in pulmonary hypertension. eHealthMe is studying from 94,041 Letairis users. Check the latest studies of Letairis.

On Jul, 19, 2026

23 people who take Nicotine and Letairis together, and have interactions are studied.

Nicotine and Letairis drug interactions.

What are the common drug interactions of Nicotine and Letairis, by gender? *:

female:

Chest pain
Cough
Hypersensitivity
Hypoxia (low oxygen in tissues)
Muscle spasms (muscle contraction)
Muscle twitching
Neuralgia (pain in one or more nerves)
Dyspnoea (difficult or laboured respiration)
Pancreatitis (inflammation of pancreas)
Pseudocyst (pathological collection of fluid)

male:

Abasia (inability to walk)
Arthralgia (joint pain)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Cardiac disorder
Diarrhoea
Nasopharyngitis (inflammation of the nasopharynx)
Right ventricular failure (right half of the heart fails to work)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Death
Femur fracture

What are the common drug interactions of Nicotine and Letairis, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Abasia (inability to walk)
Arthralgia (joint pain)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Femur fracture
Pain in extremity
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Cardiac disorder

10-19:

n/a

20-29:

n/a

30-39:

Right ventricular failure (right half of the heart fails to work)

40-49:

Muscle spasms (muscle contraction)
Muscle twitching
Neuralgia (pain in one or more nerves)
Cough
Headache (pain in head)
Hypersensitivity

50-59:

Acute respiratory failure
Multi-organ failure (multisystem organ failure)
Pancreatitis (inflammation of pancreas)
Pseudocyst (pathological collection of fluid)
Respiratory failure (inadequate gas exchange by the respiratory system)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)

60+:

Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 15 people, 65.22%
The Flu (the flu is caused by an influenza virus): 2 people, 8.70%
Nasopharyngitis (inflammation of the nasopharynx): 2 people, 8.70%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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