Nicotine and Quartette drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nicotine (nicotine) and Quartette (ethinyl estradiol; levonorgestrel). Common drug interactions include suicidal ideation among females.

The phase IV clinical study analyzes what interactions people have when they take Nicotine and Quartette. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Quartette?

Quartette has active ingredients of ethinyl estradiol; levonorgestrel. eHealthMe is studying from 79 Quartette users. Check the latest studies of Quartette.



On May, 11, 2026

12 people who take Nicotine and Quartette together, and have interactions are studied.

Nicotine and Quartette drug interactions.

What are the common drug interactions of Nicotine and Quartette, by gender? *:

female:

  1. Suicidal ideation
  2. Fatigue (feeling of tiredness)
  3. Emotional disorder
  4. Incontinence (lack of moderation or self-control)
  5. Irritability
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  8. Borderline personality disorder
  9. Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
  10. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)

male:

n/a

What are the common drug interactions of Nicotine and Quartette, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Borderline personality disorder
  2. Fatigue (feeling of tiredness)
  3. Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
  4. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  5. Sleep attacks
  6. Suicidal ideation
  7. Victim of abuse
  8. Bedridden
  9. Memory impairment

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 100.00%

* Approximation only. Some reports may have incomplete information.

Do you take Nicotine and Quartette?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nicotine and Quartette:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nicotine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Quartette:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nicotine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Quartette and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nicotine and ethinyl estradiol; levonorgestrel (the active ingredients of Nicotine and Quartette, respectively), and Nicotine and Quartette (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: