Nicotine and Roflumilast drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nicotine (nicotine) and Roflumilast (roflumilast). Common drug interactions include asthma among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Nicotine and Roflumilast. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Nicotine?

Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.

What is Roflumilast?

Roflumilast has active ingredients of roflumilast. eHealthMe is studying from 2,247 Roflumilast users. Check the latest studies of Roflumilast.

On Jul, 23, 2026

20 people who take Nicotine and Roflumilast together, and have interactions are studied.

Nicotine and Roflumilast drug interactions.

What are the common drug interactions of Nicotine and Roflumilast, by gender? *:

female:

Asthma
Dyspnoea (difficult or laboured respiration)
Influenza
Nasopharyngitis (inflammation of the nasopharynx)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Respiratory gas exchange disorder (gas exchange disease of respiratory system)
Sneezing
Wheezing (a high-pitched whistling sound made while you breath)
Cough
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Obstruction
Pain in extremity
Productive cough
Sinus congestion (blockage of sinus)
Skin exfoliation (removal of the oldest dead skin cells)
Skin fissures (a crack in the skin)

What are the common drug interactions of Nicotine and Roflumilast, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Drug ineffective
Headache (pain in head)

60+:

Dyspnoea (difficult or laboured respiration)
Cough
Productive cough
Hypoacusis (loss of hearing)
Lower respiratory tract infection
Mycobacterium test positive
Neutrophilia
Sinus disorder (disease of sinus)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

What are the existing conditions these people have? *

Asthma: 8 people, 40.00%
Sinusitis (inflammation of sinus): 8 people, 40.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 30.00%
Back Pain: 2 people, 10.00%
Hypokalemia (low potassium): 1 person, 5.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 5.00%
Hepatocellular Carcinoma (liver cancer): 1 person, 5.00%
High Blood Pressure: 1 person, 5.00%
Hiv Infection: 1 person, 5.00%
Stress And Anxiety: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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