Nicotine and Zestoretic drug interactions - a phase IV clinical study of FDA data
Summary:
The phase IV clinical study analyzes what interactions people have when they take Nicotine and Zestoretic. It is created by eHealthMe based on reports of 4 people who take the same drugs from the FDA, and is updated regularly.
What is Nicotine?
Nicotine has active ingredients of nicotine. It is often used in quit smoking. eHealthMe is studying from 20,443 Nicotine users. Check the latest studies of Nicotine.
What is Zestoretic?
Zestoretic has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 4,342 Zestoretic users. Check the latest studies of Zestoretic.
4 people who take Nicotine and Zestoretic together, and have interactions are studied.

What are the common drug interactions of Nicotine and Zestoretic, by gender? *:
female:
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Gastric ulcer haemorrhage (bleeding ulcer of stomach)
- Haemorrhagic anaemia (anaemia due to excessive bleeding)
- Pneumonia
male:
- Abdominal abscess (collection of pus in abdomen)
- Abdominal distension
- Chest pain
- Chills (felling of cold)
- Cholecystitis (infection of gallbladder)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Constipation
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
What are the common drug interactions of Nicotine and Zestoretic, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Gastric ulcer haemorrhage (bleeding ulcer of stomach)
- Haemorrhagic anaemia (anaemia due to excessive bleeding)
- Pneumonia
60+:
n/a
* Approximation only. Some reports may have incomplete information.
Do you take Nicotine and Zestoretic?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Nicotine (20,443 reports)
- Zestoretic (4,342 reports)
Browse all drug interactions of Nicotine and Zestoretic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nicotine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zestoretic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nicotine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zestoretic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nicotine and hydrochlorothiazide; lisinopril (the active ingredients of Nicotine and Zestoretic, respectively), and Nicotine and Zestoretic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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