Nifedipine and Effient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nifedipine (nifedipine) and Effient (prasugrel hydrochloride). Common drug interactions include death among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Nifedipine and Effient. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Nifedipine?

Nifedipine has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 53,459 Nifedipine users. Check the latest studies of Nifedipine.

What is Effient?

Effient has active ingredients of prasugrel hydrochloride. It is often used in stent. eHealthMe is studying from 9,482 Effient users. Check the latest studies of Effient.



On Jul, 23, 2026

45 people who take Nifedipine and Effient together, and have interactions are studied.

Nifedipine and Effient drug interactions.

What are the common drug interactions of Nifedipine and Effient, by gender? *:

female:

  1. Death
  2. Abdominal pain upper
  3. Arthralgia (joint pain)
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Cardiac failure congestive
  6. Carotid arteriosclerosis (plaque deposition in artery)
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Chronic kidney disease
  9. Dementia (madness)
  10. Gastritis (inflammation of stomach)

male:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Rectal haemorrhage (bleeding from anus)
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Erythema (redness of the skin)
  8. Muscular weakness (muscle weakness)
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Eye haemorrhage (bleeding in the eye)

What are the common drug interactions of Nifedipine and Effient, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  6. Arrhythmia (irregular heartbeat)
  7. Blood triglycerides increased
  8. Cardiac failure congestive
  9. Cardiomegaly (increased size of heart than normal)
  10. Cardiomyopathy (weakening of the heart muscle)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Abdominal pain upper
  7. Haemorrhage intracranial (bleeding within the skull)

60+:

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  2. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  3. Muscular weakness (muscle weakness)
  4. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  5. Blood glucose decreased
  6. Blood glucose increased
  7. Carotid arteriosclerosis (plaque deposition in artery)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Death
  10. Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 15 people, 33.33%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 22.22%
  3. Chest Pain: 6 people, 13.33%
  4. Insomnia (sleeplessness): 6 people, 13.33%
  5. Urinary Tract Infection: 5 people, 11.11%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 11.11%
  7. Diarrhea: 5 people, 11.11%
  8. Dyspnea (difficult or laboured breathing): 5 people, 11.11%
  9. Fever: 5 people, 11.11%
  10. Anaemia (lack of blood): 5 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Nifedipine and Effient?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nifedipine and Effient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nifedipine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Effient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nifedipine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Effient and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine and prasugrel hydrochloride (the active ingredients of Nifedipine and Effient, respectively), and Nifedipine and Effient (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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