Nipride and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nipride (sodium nitroprusside) and Digoxin (digoxin). Common drug interactions include coronary artery disease among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Nipride and Digoxin. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Nipride?

Nipride has active ingredients of sodium nitroprusside. eHealthMe is studying from 313 Nipride users. Check the latest studies of Nipride.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.



On Jul, 09, 2026

46 people who take Nipride and Digoxin together, and have interactions are studied.

Nipride and Digoxin drug interactions.

What are the common drug interactions of Nipride and Digoxin, by gender? *:

female:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Death
  3. Blood urea increased
  4. Carotid artery disease
  5. Heart rate increased
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  8. Mitral valve incompetence (inefficient heart valve)
  9. Pain in extremity
  10. Renal impairment (severely reduced kidney function)

male:

  1. Pain
  2. Anxiety
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Acute respiratory failure
  5. Confusional state
  6. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  7. Insomnia (sleeplessness)
  8. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  9. Blindness cortical
  10. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the common drug interactions of Nipride and Digoxin, by age (0-1 to 60+)? *:

0-1:

  1. Activities of daily living impaired
  2. Injury
  3. Abdominal distension
  4. Acidosis (build-up of carbon dioxide in the blood)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anuria (failure of the kidneys to produce urine)
  7. Anxiety
  8. Aortic valve incompetence
  9. Apnoea (suspension of external breathing)
  10. Arrhythmia (irregular heartbeat)

2-9:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Emotional disorder
  5. Fear
  6. Injury
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Necrotising colitis (inflammation in the intestines (usually the colon) that can be life-threatening)
  9. Nodal arrhythmia (an irregular heart beat originating from within the atrioventricular node)
  10. Pain

10-19:

n/a

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Death
  4. Depression
  5. Emotional distress
  6. Fear
  7. Injury
  8. Multi-organ failure (multisystem organ failure)
  9. Pain
  10. Renal failure (kidney dysfunction)

30-39:

  1. Abdominal pain
  2. Cardiogenic shock (inadequate circulation of blood)
  3. Cough
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Ear infection
  6. Haematoma (collection of blood outside the blood vessels)
  7. Hyperkalaemia (damage to or disease of the kidney)
  8. Insomnia (sleeplessness)
  9. Pruritus (severe itching of the skin)
  10. Respiratory failure (inadequate gas exchange by the respiratory system)

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Death
  4. Fear
  5. Injury
  6. Pain
  7. Renal failure (kidney dysfunction)
  8. Depression
  9. Emotional distress
  10. Multi-organ failure (multisystem organ failure)

50-59:

  1. Renal impairment (severely reduced kidney function)
  2. Stress
  3. Blindness
  4. Injury
  5. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  6. Renal failure acute (rapid kidney dysfunction)
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Emotional distress
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Pain

60+:

  1. Injury
  2. Pain
  3. Atelectasis (partial or complete collapse of the lung)
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Pleural effusion (water on the lungs)
  6. Ventricular fibrillation (abnormally irregular heart rhythm)
  7. Blood urea increased
  8. Carotid artery disease
  9. Heart rate increased
  10. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

What are the existing conditions these people have? *

  1. Diabetes: 5 people, 10.87%
  2. Stress And Anxiety: 4 people, 8.70%
  3. Oedema Peripheral (superficial swelling): 4 people, 8.70%
  4. Immunodeficiency Disorders: 4 people, 8.70%
  5. Hypoglycemia (low blood sugar): 4 people, 8.70%
  6. Hypertriglyceridaemia (excess of triglycerides in the blood): 4 people, 8.70%
  7. High Blood Pressure: 4 people, 8.70%
  8. Cardiac Failure Congestive: 4 people, 8.70%
  9. Otitis (ear infection): 3 people, 6.52%
  10. Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

Do you take Nipride and Digoxin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nipride and Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nipride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nipride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Digoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on sodium nitroprusside and digoxin (the active ingredients of Nipride and Digoxin, respectively), and Nipride and Digoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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