Nitro-dur and Spiriva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitro-dur (nitroglycerin) and Spiriva (tiotropium bromide monohydrate). Common drug interactions include fall among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Nitro-dur and Spiriva. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Nitro-dur?

Nitro-dur has active ingredients of nitroglycerin. eHealthMe is studying from 2,414 Nitro-dur users. Check the latest studies of Nitro-dur.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

67 people who take Nitro-dur and Spiriva together, and have interactions are studied.

Nitro-dur and Spiriva drug interactions.

What are the common drug interactions of Nitro-Dur and Spiriva, by gender? *:

female:

Fall
Insomnia (sleeplessness)
Vision blurred
Vomiting
Anaemia (lack of blood)
Arthralgia (joint pain)
Atopy (a genetic disposition to develop an allergic reaction)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blindness
Blood pressure systolic increased

male:

Pneumonia
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Wheezing (a high-pitched whistling sound made while you breath)
Malaise (a feeling of general discomfort or uneasiness)
Asthenia (weakness)
Chest pain
Death
Arthralgia (joint pain)
Chills (felling of cold)

What are the common drug interactions of Nitro-Dur and Spiriva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug hypersensitivity
Dysphonia (speech disorder attributable to a disorder of phonation)
Essential hypertension (primary hypertension)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperchlorhydria (gastric acid levels are higher in stomach)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Insomnia (sleeplessness)
Intervertebral disc degeneration (spinal disc degeneration)

50-59:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bradycardia (abnormally slow heart action)

60+:

Pneumonia
Dyspnoea (difficult or laboured respiration)
Cardiac disorder
Fall
Hip fracture
Nausea (feeling of having an urge to vomit)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Arthralgia (joint pain)
Blood pressure diastolic decreased

What are the existing conditions these people have? *

Asthma: 15 people, 22.39%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 11.94%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 10.45%
Pain: 6 people, 8.96%
Sleep Disorder: 4 people, 5.97%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 5.97%
Nausea (feeling of having an urge to vomit): 4 people, 5.97%
Muscle Spasms (muscle contraction): 4 people, 5.97%
Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 4 people, 5.97%
Dyspnea (difficult or laboured breathing): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

Do you take Nitro-dur and Spiriva?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously