Nitroglycerin and Covera-hs drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nitroglycerin (nitroglycerin) and Covera-hs (verapamil hydrochloride). Common drug interactions include hypotension among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Nitroglycerin and Covera-hs. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Nitroglycerin?
Nitroglycerin has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 52,884 Nitroglycerin users. Check the latest studies of Nitroglycerin.
What is Covera-hs?
Covera-hs has active ingredients of verapamil hydrochloride. eHealthMe is studying from 823 Covera-hs users. Check the latest studies of Covera-hs.
13 people who take Nitroglycerin and Covera-hs together, and have interactions are studied.

What are the common drug interactions of Nitroglycerin and Covera-Hs, by gender? *:
female:
- Hypotension (abnormally low blood pressure)
- Cardiac tamponade (fluid accumulates in heart covering)
- Thromboembolism (obstruction of artery by blood clot)
- Acidosis (build-up of carbon dioxide in the blood)
- Acute circulatory failure (shock)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Haemoglobin decreased
- Haemorrhage (bleeding)
- Multi-organ failure (multisystem organ failure)
- Ventricular fibrillation (abnormally irregular heart rhythm)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Cardioactive drug level above therapeutic
- Cardioactive drug level below therapeutic
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
- Heart rate irregular
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
What are the common drug interactions of Nitroglycerin and Covera-Hs, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood pressure increased
- Blood urea increased
- Brain natriuretic peptide increased
- Cardiac failure congestive
- Cardioactive drug level above therapeutic
- Cardioactive drug level below therapeutic
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dyspnoea (difficult or laboured respiration)
- Emotional distress
50-59:
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Chronic kidney disease
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hepatic failure (liver failure)
- Hepatic neoplasm malignant (liver cancer)
- Liver fatty (fat deposition of liver)
- Metastases to large intestine (cancer spreads to large intestine)
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
- Renal failure (kidney dysfunction)
60+:
- Cardiac tamponade (fluid accumulates in heart covering)
- Hypotension (abnormally low blood pressure)
- Anaemia (lack of blood)
- Arterial rupture
- Atrioventricular block (heart block)
- Atrioventricular block complete (heart block complete)
- Blood pressure increased
- Cardiac disorder
- Cardiac failure
- Cardiac fibrillation (uncontrolled muscle contraction of heart)
What are the existing conditions these people have? *
- High Blood Pressure: 4 people, 30.77%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 30.77%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 30.77%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 23.08%
- Diabetes: 3 people, 23.08%
- Pain: 3 people, 23.08%
- Oedema (fluid collection in tissue): 3 people, 23.08%
- Muscle Spasms (muscle contraction): 3 people, 23.08%
- High Blood Cholesterol: 3 people, 23.08%
- Inflammation: 3 people, 23.08%
* Approximation only. Some reports may have incomplete information.
Do you take Nitroglycerin and Covera-hs?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Nitroglycerin (52,884 reports)
- Covera-hs (823 reports)
Browse all drug interactions of Nitroglycerin and Covera-hs:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Nitroglycerin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Covera-hs:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nitroglycerin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Covera-hs and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on nitroglycerin and verapamil hydrochloride (the active ingredients of Nitroglycerin and Covera-hs, respectively), and Nitroglycerin and Covera-hs (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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