Nitroglycerin and Diastat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitroglycerin (nitroglycerin) and Diastat (diazepam). Common drug interactions include constipation among females and cognitive disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Nitroglycerin and Diastat. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Nitroglycerin?

Nitroglycerin has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 52,884 Nitroglycerin users. Check the latest studies of Nitroglycerin.

What is Diastat?

Diastat has active ingredients of diazepam. eHealthMe is studying from 2,104 Diastat users. Check the latest studies of Diastat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

15 people who take Nitroglycerin and Diastat together, and have interactions are studied.

Nitroglycerin and Diastat drug interactions.

What are the common drug interactions of Nitroglycerin and Diastat, by gender? *:

female:

Constipation
Creatinine renal clearance decreased
Depressed level of consciousness
Drug abuse
Dyspnoea (difficult or laboured respiration)
Fall
Hypotension (abnormally low blood pressure)
Mobility decreased (ability to move is reduced)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Overdose

male:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Decreased appetite
Diarrhoea
Left ventricular failure (left ventricle fails to contract forcefully)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Speech disorder

What are the common drug interactions of Nitroglycerin and Diastat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Copper deficiency
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypersomnia (excessive daytime sleepiness (eds))
Infection
Nausea (feeling of having an urge to vomit)
Pneumonia
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abdominal discomfort

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Balance disorder
Mobility decreased (ability to move is reduced)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Overdose
Pain
Sedation
Decreased appetite
Diarrhoea
Left ventricular failure (left ventricle fails to contract forcefully)

What are the existing conditions these people have? *

Adjustment Disorder: 9 people, 60.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 26.67%
Angina Unstable (chest pain due to ischemia of the heart muscle- unstable): 4 people, 26.67%
Stable Angina (a constant chest pain): 4 people, 26.67%
Insomnia (sleeplessness): 4 people, 26.67%
High Blood Pressure: 4 people, 26.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 13.33%
Asthma: 2 people, 13.33%
Bladder Disorder: 2 people, 13.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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