Coumadin and Metamorphopsia - a phase IV clinical study of FDA data

Summary:

Metamorphopsia is reported as a side effect among people who take Coumadin (warfarin sodium), especially for people who are female, 60+ old, also take Digoxin, and have Heart rate irregular.

The phase IV clinical study analyzes which people have Metamorphopsia when taking Coumadin. It is created by eHealthMe based on reports of 128,882 people who have side effects when taking Coumadin from the FDA, and is updated regularly.

What is Coumadin?

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 133,228 Coumadin users. Check the latest studies of Coumadin.

What is Metamorphopsia?

Metamorphopsia (a type of distorted vision in which a grid of straight lines appears wavy and parts of the grid may appear blank) is found to be associated with 207 drugs and 368 conditions by eHealthMe. Check the latest studies of Metamorphopsia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

128,882 people reported to have side effects when taking Coumadin.
Among them, 11 people (0.01%) have Metamorphopsia.

Could Coumadin cause Metamorphopsia?

Among these 11 people:

What is the gender of people who have Metamorphopsia when taking Coumadin? *

  • female: 54.55 %
  • male: 45.45 %

What is the age of people who have Metamorphopsia when taking Coumadin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Coumadin? *

  1. Lucentis: 3 people, 27.27%
  2. Folic Acid: 3 people, 27.27%
  3. Nexium: 3 people, 27.27%
  4. Pantoprazole: 3 people, 27.27%
  5. Plaquenil: 3 people, 27.27%
  6. Protonix: 3 people, 27.27%
  7. Lipitor: 3 people, 27.27%
  8. Toprol-Xl: 3 people, 27.27%
  9. Fosamax: 3 people, 27.27%
  10. Digoxin: 3 people, 27.27%

What are other side effects people have besides Metamorphopsia? *

  1. Visual Impairment: 7 people, 63.64%
  2. Headache (pain in head): 4 people, 36.36%
  3. Weight Decreased: 3 people, 27.27%
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 27.27%
  5. Drug Ineffective: 3 people, 27.27%
  6. Leukocytoclastic Vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura): 3 people, 27.27%
  7. Skin - Clammy: 3 people, 27.27%
  8. Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 27.27%
  9. Pancreatitis (inflammation of pancreas): 3 people, 27.27%
  10. Vision Blurred: 3 people, 27.27%

What are the existing conditions these people have? *

  1. Heart Rate Irregular: 3 people, 27.27%
  2. Prostate Cancer: 2 people, 18.18%
  3. Pain: 2 people, 18.18%
  4. Metastases To Bone (cancer spreads to bone): 2 people, 18.18%
  5. Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 2 people, 18.18%
  6. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 18.18%
  7. Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 1 person, 9.09%
  8. Diabetic Eye Disease: 1 person, 9.09%
  9. Asthma: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Coumadin and have Metamorphopsia?

- Check whether Metamorphopsia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Coumadin:

Metamorphopsia treatments and more:

How severe was Metamorphopsia and when was it recovered:

Expand to all the drugs that have ingredients of warfarin sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coumadin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Metamorphopsia:

Browse all the conditions that are associated with Metamorphopsia:


How the study uses the data?

The study uses data from the FDA. It is based on warfarin sodium (the active ingredients of Coumadin) and Coumadin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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