Nitroglycerin and Lotronex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitroglycerin (nitroglycerin) and Lotronex (alosetron hydrochloride). Common drug interactions include weight decreased among females and abnormal dreams among males.

The phase IV clinical study analyzes what interactions people have when they take Nitroglycerin and Lotronex. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Nitroglycerin?

Nitroglycerin has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 52,884 Nitroglycerin users. Check the latest studies of Nitroglycerin.

What is Lotronex?

Lotronex has active ingredients of alosetron hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 6,841 Lotronex users. Check the latest studies of Lotronex.



On Jul, 06, 2026

41 people who take Nitroglycerin and Lotronex together, and have interactions are studied.

Nitroglycerin and Lotronex drug interactions.

What are the common drug interactions of Nitroglycerin and Lotronex, by gender? *:

female:

  1. Weight decreased
  2. Pyrexia (fever)
  3. Dehydration (dryness resulting from the removal of water)
  4. Diarrhoea haemorrhagic (bloody diarrhoea)
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Abdominal pain lower
  9. Colitis (inflammation of colon)
  10. Nausea (feeling of having an urge to vomit)

male:

  1. Abnormal dreams
  2. Arthralgia (joint pain)
  3. Ear pain
  4. Irritability
  5. Neuropathy (damage to nerves)
  6. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  7. Personality disorder
  8. Pharyngolaryngeal pain
  9. Rectal haemorrhage (bleeding from anus)
  10. Speech disorder

What are the common drug interactions of Nitroglycerin and Lotronex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abnormal dreams
  2. Arthralgia (joint pain)
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Confusional state
  5. Dehydration (dryness resulting from the removal of water)
  6. Disturbance in attention
  7. Dizziness
  8. Drug abuser
  9. Drug ineffective
  10. Ear pain

40-49:

  1. Asthenia (weakness)
  2. Constipation
  3. Fatigue (feeling of tiredness)
  4. Faecaloma (hard mass of fecal matter)
  5. Painful defaecation
  6. Nausea (feeling of having an urge to vomit)
  7. Abdominal pain
  8. Abdominal pain lower
  9. Acute respiratory distress syndrome
  10. Colon spastic (stiffness of colon)

50-59:

  1. Vitamin b12 deficiency
  2. Constipation
  3. Abdominal distension
  4. Abdominal pain
  5. Colitis (inflammation of colon)
  6. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  7. Staphylococcal infection (an infection with staphylococcus bacteria)
  8. Vomiting
  9. Abdominal pain lower
  10. Diarrhoea

60+:

  1. Diarrhoea
  2. Pyrexia (fever)
  3. Vomiting
  4. Aortic valve sclerosis (narrowing of the aortic valve)
  5. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  6. Mitral valve incompetence (inefficient heart valve)
  7. Pulmonary valve incompetence
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Tricuspid valve incompetence (inefficient heart valve)
  10. Upper respiratory tract infection

What are the existing conditions these people have? *

  1. Pain: 4 people, 9.76%
  2. Diarrhea: 4 people, 9.76%

* Approximation only. Some reports may have incomplete information.

Do you take Nitroglycerin and Lotronex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nitroglycerin and Lotronex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitroglycerin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lotronex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitroglycerin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lotronex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin and alosetron hydrochloride (the active ingredients of Nitroglycerin and Lotronex, respectively), and Nitroglycerin and Lotronex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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