Nitrol and Glucophage drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrol (nitroglycerin) and Glucophage (metformin hydrochloride). Common drug interactions include gastrointestinal haemorrhage among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrol and Glucophage. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrol?

Nitrol has active ingredients of nitroglycerin. eHealthMe is studying from 3,069 Nitrol users. Check the latest studies of Nitrol.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

33 people who take Nitrol and Glucophage together, and have interactions are studied.

Nitrol and Glucophage drug interactions.

What are the common drug interactions of Nitrol and Glucophage, by gender? *:

female:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal distension
Acute myocardial infarction (acute heart attack)
Acute sinusitis
Anaemia of chronic disease
Asthenia (weakness)
Back pain
Bacterial sepsis
Blood pressure inadequately controlled

male:

Chest pain
Anxiety
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute myocardial infarction (acute heart attack)
Aggression
Alcoholic
Angina pectoris (chest pain due to ischemia of the heart muscle)
Arthralgia (joint pain)
Asthenia (weakness)
Asthma

What are the common drug interactions of Nitrol and Glucophage, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetic gastropathy (gastric neuromuscular dysfunction in diabetes mellitus)
Metabolic syndrome (a combination of the medical disorders that, when occurring together, increase the risk of developing cardiovascular disease)

40-49:

Burning sensation
Feeling hot
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Pain

50-59:

Apnoeic attack
Blood pressure immeasurable
Blood pressure inadequately controlled
Blood pressure increased
Chest pain
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Dyspnoea (difficult or laboured respiration)
Haemoglobin decreased
Panic attack
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

60+:

Chest pain
Pneumonia
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute myocardial infarction (acute heart attack)
Aggression
Alcoholic
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anxiety
Arthralgia (joint pain)
Attention-seeking behaviour

What are the existing conditions these people have? *

Type 2 Diabetes: 6 people, 18.18%
Depression: 5 people, 15.15%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 12.12%
High Blood Pressure: 4 people, 12.12%
Stress And Anxiety: 3 people, 9.09%
Stable Angina (a constant chest pain): 3 people, 9.09%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 9.09%
Chest Pain: 3 people, 9.09%
Sleep Disorder: 2 people, 6.06%
Pain: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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