Nitrostat and Fiorinal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrostat (nitroglycerin) and Fiorinal (aspirin; butalbital; caffeine). Common drug interactions include coronary artery disease among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrostat and Fiorinal. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

What is Fiorinal?

Fiorinal has active ingredients of aspirin; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 2,714 Fiorinal users. Check the latest studies of Fiorinal.



On Jul, 15, 2026

17 people who take Nitrostat and Fiorinal together, and have interactions are studied.

Nitrostat and Fiorinal drug interactions.

What are the common drug interactions of Nitrostat and Fiorinal, by gender? *:

female:

  1. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  2. Diabetes mellitus inadequate control
  3. Dizziness
  4. Drug ineffective
  5. Gastric bypass
  6. Hysterectomy
  7. Chronic kidney disease
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Renal failure (kidney dysfunction)
  10. Abdominal pain

male:

  1. Aggression
  2. Completed suicide (act of taking one's own life)
  3. Hallucination (an experience involving the perception of something not present)
  4. Overdose
  5. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  6. Anxiety
  7. Cardiac disorder
  8. Dyspepsia (indigestion)
  9. Restlessness (not able to rest)

What are the common drug interactions of Nitrostat and Fiorinal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Aggression
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Completed suicide (act of taking one's own life)
  4. Diabetes mellitus inadequate control
  5. Dizziness
  6. Drug ineffective
  7. Gastric bypass
  8. Hallucination (an experience involving the perception of something not present)
  9. Hysterectomy
  10. Overdose

60+:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Blood pressure increased
  4. Carbon dioxide increased
  5. Cardiac disorder
  6. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  7. Dyspepsia (indigestion)
  8. Flatulence (flatus expelled through the anus)
  9. Haemoglobin decreased
  10. Influenza

What are the existing conditions these people have? *

  1. Stress And Anxiety: 4 people, 23.53%
  2. High Blood Cholesterol: 3 people, 17.65%
  3. Pain: 3 people, 17.65%
  4. Gout (uric acid crystals building up in the body): 2 people, 11.76%
  5. Headache (pain in head): 2 people, 11.76%
  6. Sleep Disorder: 2 people, 11.76%
  7. High Blood Pressure: 2 people, 11.76%
  8. Carpal Tunnel Syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 2 people, 11.76%
  9. Urinary Tract Infection: 1 person, 5.88%
  10. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Nitrostat and Fiorinal?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nitrostat and Fiorinal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fiorinal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrostat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fiorinal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin and aspirin; butalbital; caffeine (the active ingredients of Nitrostat and Fiorinal, respectively), and Nitrostat and Fiorinal (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: