Nitrostat and Silvadene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nitrostat (nitroglycerin) and Silvadene (silver sulfadiazine). Common drug interactions include abdominal pain lower among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Nitrostat and Silvadene. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

What is Silvadene?

Silvadene has active ingredients of silver sulfadiazine. eHealthMe is studying from 1,161 Silvadene users. Check the latest studies of Silvadene.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 19, 2026

17 people who take Nitrostat and Silvadene together, and have interactions are studied.

Nitrostat and Silvadene drug interactions.

What are the common drug interactions of Nitrostat and Silvadene, by gender? *:

female:

  1. Abdominal pain lower
  2. Arthralgia (joint pain)
  3. Back pain
  4. Chronic kidney disease
  5. Flatulence (flatus expelled through the anus)
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Hypopharyngeal cancer
  8. Urinary tract infection
  9. Dehydration (dryness resulting from the removal of water)
  10. Disease progression

male:

  1. Cardiac failure congestive
  2. Dyspnoea (difficult or laboured respiration)
  3. Renal failure (kidney dysfunction)
  4. Cardiac arrest
  5. Chronic kidney disease
  6. Death
  7. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  8. Hypertension (high blood pressure)
  9. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  10. Renal injury (kidney injury)

What are the common drug interactions of Nitrostat and Silvadene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Hypertension (high blood pressure)
  5. Renal failure (kidney dysfunction)
  6. Renal injury (kidney injury)

50-59:

  1. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  2. Migraine (headache)
  3. Urinary tract infection

60+:

  1. Cardiac failure congestive
  2. Dyspnoea (difficult or laboured respiration)
  3. Hypovolaemia (a decreased volume of circulating blood in the body)
  4. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  5. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  6. Renal failure (kidney dysfunction)
  7. Renal impairment (severely reduced kidney function)
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Abdominal pain lower
  10. Arthralgia (joint pain)

What are the existing conditions these people have? *

  1. Wheezing (a high-pitched whistling sound made while you breath): 6 people, 35.29%
  2. Dyspnea (difficult or laboured breathing): 5 people, 29.41%
  3. Pain: 5 people, 29.41%
  4. Wound: 3 people, 17.65%
  5. Muscle Spasms (muscle contraction): 3 people, 17.65%
  6. Stress And Anxiety: 3 people, 17.65%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
  8. High Blood Cholesterol: 3 people, 17.65%
  9. Migraine (headache): 3 people, 17.65%
  10. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nitrostat and Silvadene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nitrostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Silvadene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nitrostat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Silvadene and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nitroglycerin and silver sulfadiazine (the active ingredients of Nitrostat and Silvadene, respectively), and Nitrostat and Silvadene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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