Norco and Stadol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norco (acetaminophen; hydrocodone bitartrate) and Stadol (butorphanol tartrate). Common drug interactions include neck pain among females and abnormal behaviour among males.

The phase IV clinical study analyzes what interactions people have when they take Norco and Stadol. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Norco?

Norco has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 74,063 Norco users. Check the latest studies of Norco.

What is Stadol?

Stadol has active ingredients of butorphanol tartrate. It is often used in migraine. eHealthMe is studying from 5,546 Stadol users. Check the latest studies of Stadol.

On Jul, 14, 2026

36 people who take Norco and Stadol together, and have interactions are studied.

What are the common drug interactions of Norco and Stadol, by gender? *:

female:

Neck pain
Nerve block (the interruption of signals travelling along a nerve)
Nerve compression
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Oedema peripheral (superficial swelling)
Pain in extremity
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Premature delivery
Procedural nausea
Procedural vomiting

male:

Abnormal behaviour
Aggression
Chest discomfort
Chest pain
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Communication disorder (speech and language disorder)
Cough
Croup infectious (a loud cough that resembles the barking of a seal and difficulty breathing can transfer to other)
Developmental delay
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

What are the common drug interactions of Norco and Stadol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Abnormal loss of weight
Amniotic cavity infection
Amniotic fluid volume decreased
Gastric ulcer (stomach ulcer)
Hallucination (an experience involving the perception of something not present)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperhidrosis (abnormally increased sweating)
Irritability

30-39:

Pulmonary embolism (blockage of the main artery of the lung)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Burning sensation
Drug abuser
Drug addiction
Dry eye (lack of adequate tears)
Dry mouth
Emotional distress
Erythema (redness of the skin)

40-49:

Abnormal behaviour
Dental caries
Depression
Drug dependence
Dysarthria (speech disorder)
Tooth abscess (pus formation in tooth)
Drug abuse
Drug hypersensitivity
Back injury
Drug abuser

50-59:

Bladder disorder
Blood glucose decreased
Blood glucose increased
Blood pressure increased
Burning sensation
Chills (felling of cold)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Constipation
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dehydration (dryness resulting from the removal of water)

60+:

Drug ineffective
General physical health deterioration (weak health status)
Lyme disease (a bacterial infection that is spread to humans by infected ticks)
Skin ulcer
Stomatitis (inflammation of mucous membrane of mouth)

What are the existing conditions these people have? *

Back Pain: 10 people, 27.78%
Headache (pain in head): 4 people, 11.11%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 3 people, 8.33%
Stress And Anxiety: 2 people, 5.56%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 5.56%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 5.56%
Joint Pain: 2 people, 5.56%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.56%
Abdominal Pain: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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