Norditropin and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norditropin (somatropin recombinant) and Metformin (metformin hydrochloride). Common drug interactions include diabetes mellitus inadequate control among females and ageusia among males.

The phase IV clinical study analyzes what interactions people have when they take Norditropin and Metformin. It is created by eHealthMe based on reports of 68 people who take the same drugs from the FDA, and is updated regularly.

What is Norditropin?

Norditropin has active ingredients of somatropin recombinant. It is often used in growth hormone deficiency. eHealthMe is studying from 4,920 Norditropin users. Check the latest studies of Norditropin.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

On Jul, 15, 2026

68 people who take Norditropin and Metformin together, and have interactions are studied.

Norditropin and Metformin drug interactions.

What are the common drug interactions of Norditropin and Metformin, by gender? *:

female:

Diabetes mellitus inadequate control
Drug administration error
Drug ineffective
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)
Groin pain
Heart rate increased
Hyperhidrosis (abnormally increased sweating)
Infusion site reaction
Injection site pain

male:

Ageusia (loss of taste functions of the tongue)
Anaemia (lack of blood)
Skin haemorrhage (bleeding into skin)
Skin lesion
Stomatitis (inflammation of mucous membrane of mouth)
Tongue discolouration (colour change of tongue)
Weight decreased
Tremor (trembling or shaking movements in one or more parts of your body)
Wound complication
Craniopharyngioma (a type of brain tumour derived from pituitary gland embryonic tissue)

What are the common drug interactions of Norditropin and Metformin, by age (0-1 to 60+)? *:

0-1:

Blood insulin increased
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hyperlipidaemia (presence of excess lipids in the blood)
Insulin resistance
Insulin-like growth factor increased

2-9:

Ear infection
Infusion site pain
Mastoiditis (infection of mastoid bone)
Staphylococcal infection (an infection with staphylococcus bacteria)
Weight fluctuation
Ear discomfort

10-19:

Cardiac arrest
Growth retardation (delayed growth)
Craniopharyngioma (a type of brain tumour derived from pituitary gland embryonic tissue)
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Hyperinsulinaemia (excess levels of insulin circulating in the blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Increased viscosity of bronchial secretion
Secretion discharge
Sputum discoloured
Surgery

20-29:

Urticaria (rash of round, red welts on the skin that itch intensely)
Rash

30-39:

Agitation (state of anxiety or nervous excitement)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Overdose
Scoliosis (a medical condition in which a person's spine is curved from side to side)
White blood cell count increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Hypertension (high blood pressure)

40-49:

Impaired gastric emptying
Neck injury
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

Malaise (a feeling of general discomfort or uneasiness)
Diabetes mellitus inadequate control
Diarrhoea
Epididymal enlargement (skin thickening, hydrocele, and hyperaemia)
Faecal incontinence (a lack of control over passing stool)
Injection site pain
Pancreatitis (inflammation of pancreas)
Pulmonary thrombosis (scarring in the lungs)
Skin hypertrophy (skin cells enlarges)
Testicular mass (mass on testes)

60+:

Hyperhidrosis (abnormally increased sweating)
Ageusia (loss of taste functions of the tongue)
Lower limb fracture
Skin haemorrhage (bleeding into skin)
Skin lesion
Stomatitis (inflammation of mucous membrane of mouth)
Tongue discolouration (colour change of tongue)
Weight decreased
Tremor (trembling or shaking movements in one or more parts of your body)
Wound complication

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 8.82%
Type 2 Diabetes: 5 people, 7.35%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 5 people, 7.35%
Cystic Fibrosis (disease of the secretary glands): 5 people, 7.35%

* Approximation only. Some reports may have incomplete information.

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