Norflex and Anaprox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norflex (orphenadrine citrate) and Anaprox (naproxen sodium). Common drug interactions include tendon disorder among females and myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Norflex and Anaprox. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Norflex?

Norflex has active ingredients of orphenadrine citrate. It is often used in muscle spasms. eHealthMe is studying from 1,951 Norflex users. Check the latest studies of Norflex.

What is Anaprox?

Anaprox has active ingredients of naproxen sodium. eHealthMe is studying from 1,370 Anaprox users. Check the latest studies of Anaprox.

On Jul, 03, 2026

32 people who take Norflex and Anaprox together, and have interactions are studied.

What are the common drug interactions of Norflex and Anaprox, by gender? *:

female:

Tendon disorder (disease of tendon)
Tongue dry
Acne (skin problems that cause pimples)
Aphasia (damage to the parts of the brain that control language)
Blood immunoglobulin g increased
Dizziness
Fibromyalgia (a long-term condition which causes pain all over the body)
Hypoaesthesia (reduced sense of touch or sensation)
Joint swelling
Memory impairment

male:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Insomnia (sleeplessness)
Confusional state
Constipation
Dizziness
Dyspnoea (difficult or laboured respiration)
Haematochezia (passage of stools containing blood)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Rash
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Norflex and Anaprox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Depression

20-29:

Abdominal pain
Aggression
Depression
Disturbance in attention
Hallucination, auditory (perceiving sounds without auditory stimulus)
Insomnia (sleeplessness)
Suicide attempt

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Oedema peripheral (superficial swelling)
Pain in extremity
Pulmonary embolism (blockage of the main artery of the lung)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Accident at work
Intervertebral disc protrusion (spinal disc protrusion)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)

40-49:

Connective tissue disorder (any disease that has the connective tissues of the body)
Anxiety
Ear pain
Fall
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Asthenia (weakness)
Balance disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Confusional state

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)

60+:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)

What are the existing conditions these people have? *

Hepatitis C: 10 people, 31.25%
Pain: 8 people, 25.00%
Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 5 people, 15.62%
Procedural Pain: 3 people, 9.38%
Back Injury: 3 people, 9.38%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 6.25%
Cardiac Failure Congestive: 2 people, 6.25%
Bipolar Disorder (mood disorder): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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