Norflex and Imdur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norflex (orphenadrine citrate) and Imdur (isosorbide mononitrate). Common drug interactions include angina pectoris among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Norflex and Imdur. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Norflex?

Norflex has active ingredients of orphenadrine citrate. It is often used in muscle spasms. eHealthMe is studying from 1,951 Norflex users. Check the latest studies of Norflex.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.

On Jul, 13, 2026

17 people who take Norflex and Imdur together, and have interactions are studied.

What are the common drug interactions of Norflex and Imdur, by gender? *:

female:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Arterial disorder
Blood glucose increased
Cough
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Excoriation (to tear or wear off the skin of)
Gait disturbance
Impaired gastric emptying
Injury
Lung disorder (lung disease)

male:

Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)
Renal tubular necrosis (death of kidney tubules)
Abdominal pain upper
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Balance disorder
Balanitis candida (inflammation of the glands penis by infection with candida albicans)

What are the common drug interactions of Norflex and Imdur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Wheezing (a high-pitched whistling sound made while you breath)
Abdominal pain upper
Anxiety
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Balance disorder
Balanitis candida (inflammation of the glands penis by infection with candida albicans)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac failure congestive

50-59:

Chronic kidney disease
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Nephrogenic anaemia (anaemia due to kidney disease)
Organic brain syndrome (decreased mental function due to a medical disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

60+:

Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Blood glucose increased
Chronic kidney disease
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nephrogenic anaemia (anaemia due to kidney disease)
Overdose
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)

What are the existing conditions these people have? *

Pain: 7 people, 41.18%
High Blood Cholesterol: 5 people, 29.41%
Muscle Aches (muscle pain): 4 people, 23.53%
Ill-Defined Disorder: 3 people, 17.65%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 17.65%
Cardiac Disorder: 3 people, 17.65%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 17.65%
Dizziness: 3 people, 17.65%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 17.65%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%

* Approximation only. Some reports may have incomplete information.

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