Norflex and Lipitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norflex (orphenadrine citrate) and Lipitor (atorvastatin calcium). Common drug interactions include pollakiuria among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Norflex and Lipitor. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Norflex?

Norflex has active ingredients of orphenadrine citrate. It is often used in muscle spasms. eHealthMe is studying from 1,951 Norflex users. Check the latest studies of Norflex.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,047 Lipitor users. Check the latest studies of Lipitor.

On Jul, 12, 2026

95 people who take Norflex and Lipitor together, and have interactions are studied.

What are the common drug interactions of Norflex and Lipitor, by gender? *:

female:

Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Arthralgia (joint pain)
Dysphonia (speech disorder attributable to a disorder of phonation)
Laryngitis (inflammation of the larynx)
Blood magnesium decreased
Loss of consciousness
Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
Pain
Syncope (loss of consciousness with an inability to maintain postural tone)
Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)

male:

Pain in extremity
Renal failure (kidney dysfunction)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Headache (pain in head)
Muscular weakness (muscle weakness)
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal pain
Abdominal pain upper
Abdominal tenderness
Agitation (state of anxiety or nervous excitement)

What are the common drug interactions of Norflex and Lipitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug addiction
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Impaired work ability
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)

40-49:

Abasia (inability to walk)
Pruritus (severe itching of the skin)
Alanine aminotransferase increased
Arthralgia (joint pain)
Aspartate aminotransferase increased
Cardiac disorder
Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
Cerebral artery embolism (sudden blocking of an artery by a clot or foreign material)
Cerebral cyst (fluid filled tumour of brain)
Chronic kidney disease

50-59:

Viral labyrinthitis (viral inflammation of the inner ear)
Blood glucose increased
Depression
Diarrhoea
Headache (pain in head)
Injection site haematoma (localized swelling filled with blood at injection site)
Pain
Vomiting
Abdominal distension
Abdominal pain

60+:

Chest pain
Abscess (pus)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Urinary tract infection
Dysphonia (speech disorder attributable to a disorder of phonation)
Laryngitis (inflammation of the larynx)
Blood magnesium decreased
Arthralgia (joint pain)
Haemangioma of liver (noncancerous, abnormally dense collections of dilated small blood vessels that may occur in liver)
Loss of consciousness

What are the existing conditions these people have? *

Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 22 people, 23.16%
Pain: 15 people, 15.79%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 13.68%
High Blood Pressure: 12 people, 12.63%
Vaginal Prolapse (portion of the vaginal canal protruding (prolapsing) from the opening of the vagina): 11 people, 11.58%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 11.58%
Depression: 9 people, 9.47%
Sleep Disorder: 6 people, 6.32%
Multiple Myeloma (cancer of the plasma cells): 6 people, 6.32%
Nausea (feeling of having an urge to vomit): 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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