Normodyne and Cozaar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Normodyne (labetalol hydrochloride) and Cozaar (losartan potassium). Common drug interactions include convulsion among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Normodyne and Cozaar. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Normodyne?

Normodyne has active ingredients of labetalol hydrochloride. eHealthMe is studying from 858 Normodyne users. Check the latest studies of Normodyne.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

On Jul, 13, 2026

62 people who take Normodyne and Cozaar together, and have interactions are studied.

What are the common drug interactions of Normodyne and Cozaar, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Osteonecrosis of jaw (death of bone of jaw)
Pyrexia (fever)
Renal impairment (severely reduced kidney function)
Sinusitis (inflammation of sinus)
Tremor (trembling or shaking movements in one or more parts of your body)
Actinomycosis (infection that causes sores, or abscesses)
Bone pain

male:

Death
Cardiac disorder
Chest discomfort
Cough
Dry gangrene (diminished blood supply due to vascular problems)
Dyspepsia (indigestion)
Extremity necrosis (death of body tissue of arms and legs)
Fatigue (feeling of tiredness)
Hyperlipidaemia (presence of excess lipids in the blood)
Lethargy (tiredness)

What are the common drug interactions of Normodyne and Cozaar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Device related infection
Hypertensive emergency

10-19:

Appendicitis (inflammation of the appendix)

20-29:

Fatigue (feeling of tiredness)

30-39:

Renal impairment (severely reduced kidney function)
Accelerated hypertension (significant hypertension)
Gastroenteritis (inflammation of stomach and intestine)
Pericardial effusion (fluid around the heart)
Abdominal discomfort
Abdominal pain
Arthralgia (joint pain)
Back pain
Diarrhoea
Dizziness

40-49:

Actinomycosis (infection that causes sores, or abscesses)
Anaemia (lack of blood)
Anxiety
Bone disorder
Bone pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Candidiasis (candidiasis or thrush is a fungal infection)
Cerebral atrophy (decrement in size of brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Constipation

50-59:

Emotional distress
Hyperlipidaemia (presence of excess lipids in the blood)
Myalgia (muscle pain)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Oedema (fluid collection in tissue)
Pain
Psoriasis (immune-mediated disease that affects the skin)
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

60+:

Cerebral haemorrhage (bleeding within the brain)
Death
Chest pain
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperglycaemia (high blood sugar)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Pain: 12 people, 19.35%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 9.68%
Breast Cancer: 6 people, 9.68%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.06%
Neuralgia (pain in one or more nerves): 4 people, 6.45%
Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 4 people, 6.45%
Diarrhea: 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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