Norpace and Protonix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norpace (disopyramide phosphate) and Protonix (pantoprazole sodium). Common drug interactions include pruritus generalised among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Norpace and Protonix. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Norpace?

Norpace has active ingredients of disopyramide phosphate. eHealthMe is studying from 1,179 Norpace users. Check the latest studies of Norpace.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

On Jul, 05, 2026

22 people who take Norpace and Protonix together, and have interactions are studied.

What are the common drug interactions of Norpace and Protonix, by gender? *:

female:

Pruritus generalised (generalized itching)
Rash
Rash macular (small, flat red spots)
Rash pruritic (redness with itching)
Red blood cell count decreased
Renal cyst (kidney cyst)
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)

male:

Asthenia (weakness)
Pulmonary oedema (fluid accumulation in the lungs)
Post procedural infection
Ageusia (loss of taste functions of the tongue)
Back pain
Chest discomfort
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Diarrhoea

What are the common drug interactions of Norpace and Protonix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Blood iron decreased
Blood magnesium decreased
Blood potassium decreased
Dehydration (dryness resulting from the removal of water)
Red blood cell count decreased

60+:

Abdominal pain
Decreased appetite
Syncope (loss of consciousness with an inability to maintain postural tone)
Heart rate decreased
Hypotension (abnormally low blood pressure)
Dizziness
Hypertrophic cardiomyopathy (a condition in which the heart muscle becomes abnormally thick)
Loss of consciousness
Post procedural infection
Vein pain

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 27.27%
Nasal Discharge (discharge from nose): 4 people, 18.18%
Multiple Myeloma (cancer of the plasma cells): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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