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Northera and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Northera (droxidopa) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include throat tightness among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Northera and Adderall. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Northera?

Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.

On Jul, 10, 2026

45 people who take Northera and Adderall together, and have interactions are studied.

Northera and Adderall drug interactions.

What are the common drug interactions of Northera and Adderall, by gender? *:

female:

  1. Throat tightness
  2. Vertigo
  3. Viral infection
  4. Acute myocardial infarction (acute heart attack)
  5. Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
  6. Catecholamines urine increased
  7. Crying
  8. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  9. Headache (pain in head)
  10. Fatigue (feeling of tiredness)

male:

  1. Dizziness
  2. Blood triglycerides increased
  3. Blood pressure increased
  4. Diarrhoea
  5. Drug intolerance (drug sensitivity)
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Hypersensitivity
  9. Hypotension (abnormally low blood pressure)
  10. Loss of consciousness

What are the common drug interactions of Northera and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Dizziness
  2. Headache (pain in head)
  3. Abdominal discomfort
  4. Blepharospasm (any abnormal contraction or twitch of the eyelid)
  5. Blood pressure increased
  6. Chest pain
  7. Confusional state
  8. Disturbance in attention
  9. Fatigue (feeling of tiredness)
  10. Hypoaesthesia (reduced sense of touch or sensation)

20-29:

  1. Extrasystoles
  2. Fatigue (feeling of tiredness)
  3. Heart rate irregular
  4. Influenza like illness
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Sluggishness (lacking alertness)
  7. Nephrolithiasis (calculi in the kidneys)
  8. Viral infection
  9. Headache (pain in head)
  10. Dizziness

30-39:

  1. Dizziness
  2. Drug ineffective
  3. Fatigue (feeling of tiredness)
  4. Flushing (the warm, red condition of human skin)
  5. Headache (pain in head)
  6. Heart rate increased
  7. Influenza like illness
  8. Joint stiffness
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Mood swings (an extreme or rapid change in mood)

40-49:

  1. Fall
  2. Asthenia (weakness)
  3. Fatigue (feeling of tiredness)
  4. Head injury
  5. Heart rate increased
  6. Hypertension (high blood pressure)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Vomiting
  9. Confusional state
  10. Feeling cold

50-59:

  1. Blood pressure decreased
  2. Nausea (feeling of having an urge to vomit)
  3. Blood pressure immeasurable
  4. Constipation
  5. Ear discomfort
  6. Hypertension (high blood pressure)
  7. Insomnia (sleeplessness)
  8. Libido increased (increased sexual urge to have sex)
  9. Loss of consciousness
  10. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

60+:

  1. Headache (pain in head)
  2. Blood pressure fluctuation
  3. Dizziness
  4. Drug intolerance (drug sensitivity)
  5. Fatigue (feeling of tiredness)
  6. Hypersensitivity
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Fall
  9. Head injury
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

  1. Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 12 people, 26.67%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 20.00%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 20.00%
  4. Hypotension (abnormally low blood pressure): 7 people, 15.56%
  5. Postural Orthostatic Tachycardia Syndrome (abnormal increase in heart rate on becoming upright): 5 people, 11.11%
  6. Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 5 people, 11.11%
  7. Parkinson's Disease: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Northera and Adderall?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Northera and Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Northera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Northera and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on droxidopa and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Northera and Adderall, respectively), and Northera and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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