Northera and Jakafi drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Northera (droxidopa) and Jakafi (ruxolitinib phosphate). Common drug interactions include anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Northera and Jakafi. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Northera?
Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.
What is Jakafi?
Jakafi has active ingredients of ruxolitinib phosphate. It is often used in primary myelofibrosis. eHealthMe is studying from 56,530 Jakafi users. Check the latest studies of Jakafi.
11 people who take Northera and Jakafi together, and have interactions are studied.
What are the common drug interactions of Northera and Jakafi, by gender? *:
female:
n/a
male:
- Anaemia (lack of blood)
- Feeling jittery
- Haemoglobin decreased
- Headache (pain in head)
- Tachyphrenia (abnormally rapid mental activity)
- Increased appetite
- Poor quality sleep
- Weight increased
- Blood pressure decreased
- Fluid overload (too much fluid in the blood)
What are the common drug interactions of Northera and Jakafi, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Platelet count increased
- Splenomegaly (enlargement of spleen)
- Haemoglobin decreased
- Anaemia (lack of blood)
- Feeling jittery
- Increased appetite
- Poor quality sleep
- Weight increased
- Blood pressure decreased
- Fluid overload (too much fluid in the blood)
60+:
- Headache (pain in head)
- Tachyphrenia (abnormally rapid mental activity)
What are the existing conditions these people have? *
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 9 people, 81.82%
- Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 7 people, 63.64%
- Diabetes: 7 people, 63.64%
- Blood Pressure Abnormal: 4 people, 36.36%
- Bleeding Disorders: 4 people, 36.36%
- Diarrhea: 2 people, 18.18%
- Hypotension (abnormally low blood pressure): 1 person, 9.09%
- Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Northera and Jakafi?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Northera and Jakafi:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Northera:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Jakafi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Northera and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Jakafi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on droxidopa and ruxolitinib phosphate (the active ingredients of Northera and Jakafi, respectively), and Northera and Jakafi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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