Norvasc and Feldene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norvasc (amlodipine besylate) and Feldene (piroxicam). Common drug interactions include asthenia among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Norvasc and Feldene. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.

What is Feldene?

Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.



On Jul, 11, 2026

81 people who take Norvasc and Feldene together, and have interactions are studied.

Norvasc and Feldene drug interactions.

What are the common drug interactions of Norvasc and Feldene, by gender? *:

female:

  1. Asthenia (weakness)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  4. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  6. Cervical cord compression (compression of spinal cord at site of cervical vertebrae)
  7. Dental caries
  8. Disability
  9. Granuloma (a small area of inflammation due to tissue injury)
  10. Hand deformity

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Photosensitivity reaction
  3. Discoid lupus erythematosus (chronic skin condition of sores with inflammation and scarring favouring the face, ears, and scalp)
  4. Dizziness
  5. Fatigue (feeling of tiredness)
  6. Hallucination (an experience involving the perception of something not present)
  7. Hypotension (abnormally low blood pressure)
  8. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  9. Pain
  10. Renal failure (kidney dysfunction)

What are the common drug interactions of Norvasc and Feldene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Back pain
  2. Cardiac failure
  3. Cardiac failure congestive
  4. Chest pain
  5. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  6. Dyspnoea exertional (breathlessness or shortness of breath)
  7. Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
  8. Hypercholesterolaemia (high levels of cholesterol in the blood)
  9. Hypertensive heart disease
  10. Hypertriglyceridaemia (excess of triglycerides in the blood)

40-49:

  1. Abdominal pain
  2. Affective disorder (mental disorder)
  3. Blood potassium decreased
  4. Chest pain
  5. Depression
  6. Dizziness
  7. Dyspepsia (indigestion)
  8. Emotional distress
  9. Epistaxis (bleed from the nose)
  10. Erythema (redness of the skin)

50-59:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Atelectasis (partial or complete collapse of the lung)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  6. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  7. Bone deformity
  8. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  9. Bone loss
  10. Bone pain

60+:

  1. Bone pain
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  3. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  4. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  5. Cervical cord compression (compression of spinal cord at site of cervical vertebrae)
  6. Dental caries
  7. Disability
  8. Fibromyalgia (a long-term condition which causes pain all over the body)
  9. Granuloma (a small area of inflammation due to tissue injury)
  10. Hand deformity

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 17.28%
  2. Diabetes: 7 people, 8.64%
  3. Pain: 5 people, 6.17%
  4. Ill-Defined Disorder: 5 people, 6.17%
  5. Back Pain: 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Norvasc and Feldene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norvasc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Feldene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Norvasc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Feldene and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate and piroxicam (the active ingredients of Norvasc and Feldene, respectively), and Norvasc and Feldene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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