Norvasc and Oramorph sr drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norvasc (amlodipine besylate) and Oramorph sr (morphine sulfate). Common drug interactions include dyspnoea among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Norvasc and Oramorph sr. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,738 Norvasc users. Check the latest studies of Norvasc.

What is Oramorph sr?

Oramorph sr has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 2,897 Oramorph sr users. Check the latest studies of Oramorph sr.



On Aug, 02, 2026

19 people who take Norvasc and Oramorph sr together, and have interactions are studied.

Norvasc and Oramorph sr drug interactions.

What are the common drug interactions of Norvasc and Oramorph Sr, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Chest pain
  3. Abdominal pain upper
  4. Cardiac failure congestive
  5. Fatigue (feeling of tiredness)
  6. Hypoxia (low oxygen in tissues)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Pneumonia
  9. Agitation (state of anxiety or nervous excitement)
  10. Arteriosclerosis (thickening and hardening of arteries)

male:

  1. Hypotension (abnormally low blood pressure)
  2. Acetabulum fracture (socket of the hip joint- fracture)
  3. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  4. Fatigue (feeling of tiredness)
  5. Hallucination (an experience involving the perception of something not present)
  6. Heart rate increased
  7. Hypoxia (low oxygen in tissues)
  8. Infection
  9. Oedema lower limb (fluid collection in tissue of lower leg)
  10. Pneumonia

What are the common drug interactions of Norvasc and Oramorph Sr, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Chest pain
  3. Cardiac failure congestive
  4. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  5. Fatigue (feeling of tiredness)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Weakness

50-59:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Chest pain

60+:

  1. Hypoxia (low oxygen in tissues)
  2. Pneumonia
  3. Anaemia (lack of blood)
  4. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  5. Arteriosclerosis (thickening and hardening of arteries)
  6. Asthenia (weakness)
  7. Asthma
  8. Atelectasis (partial or complete collapse of the lung)
  9. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  10. Atrioventricular block first degree (heart block first degree)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.26%
  2. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 5.26%
  3. Multiple Myeloma (cancer of the plasma cells): 1 person, 5.26%
  4. Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 5.26%
  5. Metastases To Bone (cancer spreads to bone): 1 person, 5.26%
  6. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 5.26%
  7. Lung Cancer Metastatic (lung cancer spreads to other parts): 1 person, 5.26%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.26%
  9. Chest Pain: 1 person, 5.26%
  10. Back Pain: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Norvasc and Oramorph sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Norvasc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oramorph sr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Norvasc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oramorph sr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate and morphine sulfate (the active ingredients of Norvasc and Oramorph sr, respectively), and Norvasc and Oramorph sr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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