Norvir and Akineton drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norvir (ritonavir) and Akineton (biperiden hydrochloride). Common drug interactions include renal failure acute among females and renal impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Norvir and Akineton. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Norvir?

Norvir has active ingredients of ritonavir. It is often used in hiv infection. eHealthMe is studying from 24,973 Norvir users. Check the latest studies of Norvir.

What is Akineton?

Akineton has active ingredients of biperiden hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 6,140 Akineton users. Check the latest studies of Akineton.

On Jul, 15, 2026

15 people who take Norvir and Akineton together, and have interactions are studied.

What are the common drug interactions of Norvir and Akineton, by gender? *:

female:

Renal failure acute (rapid kidney dysfunction)
Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
Coma (state of unconsciousness lasting more than six hours)
Electrocardiogram qt prolonged
Sedation
Abdominal pain
Decreased appetite
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Nausea (feeling of having an urge to vomit)
Vomiting

male:

Renal impairment (severely reduced kidney function)
Blood cholesterol increased
Weight increased
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood creatinine increased
Blood lactate dehydrogenase increased
Blood urea increased
Gamma-glutamyltransferase increased

What are the common drug interactions of Norvir and Akineton, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Renal impairment (severely reduced kidney function)
Blood cholesterol increased
Blood triglycerides increased
Angina pectoris (chest pain due to ischemia of the heart muscle)
Cardiac arrest
Chest pain
Electrocardiogram qt prolonged
Electrocardiogram st segment depression
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)

40-49:

Abdominal pain
Decreased appetite
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Nausea (feeling of having an urge to vomit)
Vomiting
Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection)
Confusional state
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Psychotic disorder

50-59:

Coma (state of unconsciousness lasting more than six hours)
Aids encephalopathy (malfunction of the brain as a result of hiv infection, variety of cognitive, motor, and behavioural abnormalities)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Blood pressure diastolic increased
Fall
Hepatic enzyme increased
Malaise (a feeling of general discomfort or uneasiness)
Nuclear magnetic resonance imaging brain

60+:

n/a

What are the existing conditions these people have? *

Diabetes: 3 people, 20.00%
Depression: 3 people, 20.00%
Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 2 people, 13.33%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 13.33%
Hypokalemia (low potassium): 2 people, 13.33%
Abnormal Behavior: 2 people, 13.33%
Psychotic Disorder: 1 person, 6.67%
Phobia (fear): 1 person, 6.67%
Nephropathy (damage to or disease of a kidney): 1 person, 6.67%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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