Norvir and Keflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Norvir (ritonavir) and Keflex (cephalexin). Common drug interactions include pain among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Norvir and Keflex. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Norvir?

Norvir has active ingredients of ritonavir. It is often used in hiv infection. eHealthMe is studying from 24,973 Norvir users. Check the latest studies of Norvir.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

On Jul, 31, 2026

47 people who take Norvir and Keflex together, and have interactions are studied.

What are the common drug interactions of Norvir and Keflex, by gender? *:

female:

Pain
Depression
Osteoporosis (bones weak and more likely to break)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
Pregnancy
Ankle fracture
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Fibula fracture
Maternal exposure during pregnancy (use of substance during pregnancy)

male:

Emotional distress
Pain
Osteomyelitis (infection of bone)
Bone loss
Nephrolithiasis (calculi in the kidneys)
Renal impairment (severely reduced kidney function)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Tooth fracture
Diarrhoea
Abdominal pain

What are the common drug interactions of Norvir and Keflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaemia (lack of blood)
Blood pressure increased
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Fungal infection
Staphylococcal infection (an infection with staphylococcus bacteria)
Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system)
Live birth
Placenta praevia (a condition that occurs during pregnancy when the placenta is abnormally placed, and partially or totally covers the cervix)
Pregnancy
Bone density decreased

30-39:

Emotional distress
Pain
Bone density decreased
Depression
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Arthralgia (joint pain)
Bone loss
Fracture
Fractured sacrum
Gait disturbance

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Bone density decreased
Chronic kidney disease
Renal failure (kidney dysfunction)
Diarrhoea
Depression
Aids related complication

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Renal failure (kidney dysfunction)
Bone density decreased
Chronic kidney disease
Osteoporosis (bones weak and more likely to break)
Ankle fracture
Depression

60+:

Anaemia (lack of blood)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Haemoglobin decreased
Influenza
Nasopharyngitis (inflammation of the nasopharynx)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Pneumonia
Staphylococcus test positive
Blood pressure increased

What are the existing conditions these people have? *

Epidural Anaesthesia: 6 people, 12.77%
Pain: 5 people, 10.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 10.64%
Back Pain: 5 people, 10.64%
Indigestion: 4 people, 8.51%
High Blood Pressure: 4 people, 8.51%
Erosive Oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time): 4 people, 8.51%
Multiple Myeloma (cancer of the plasma cells): 3 people, 6.38%
Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

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