Norvir and Neupogen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Norvir (ritonavir) and Neupogen (filgrastim). Common drug interactions include cytolytic hepatitis among females and lipodystrophy acquired among males.
The phase IV clinical study analyzes what interactions people have when they take Norvir and Neupogen. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.
What is Norvir?
Norvir has active ingredients of ritonavir. It is often used in hiv infection. eHealthMe is studying from 24,973 Norvir users. Check the latest studies of Norvir.
What is Neupogen?
Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.
98 people who take Norvir and Neupogen together, and have interactions are studied.

What are the common drug interactions of Norvir and Neupogen, by gender? *:
female:
- Cytolytic hepatitis (dissolution or destruction of a liver cell)
- Nephrolithiasis (calculi in the kidneys)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Drug eruption (adverse drug reaction of the skin)
- Haemorrhage (bleeding)
- Mastoiditis (infection of mastoid bone)
- Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
- Vulvovaginal candidiasis (vulvovaginal infection by fungi)
- Abdominal discomfort
- Abdominal pain
male:
- Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
- Diplopia (double vision)
- Abdominal pain
- Anxiety
- Back pain
- Headache (pain in head)
- Renal failure acute (rapid kidney dysfunction)
- Weight decreased
- Chest pain
- Extraocular muscle paresis (nerve paralysis outside of eye tissue)
What are the common drug interactions of Norvir and Neupogen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Abdominal distension
- Abdominal pain
- Ascites (accumulation of fluid in the abdominal cavity)
- Bacterial infection
- Herpes simplex (herpes simplex is a common viral infection)
- Hypertension (high blood pressure)
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Injection site infection
- Otitis media (inflammation of the middle ear)
- Parasitic infection intestinal
10-19:
- Anxiety
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Ketoacidosis (high concentrations of ketone bodies in blood)
- Sweating increased (excess sweating)
20-29:
- Drug eruption (adverse drug reaction of the skin)
- Haemorrhage (bleeding)
- Mastoiditis (infection of mastoid bone)
- Mucosal inflammation (infection of mucous membrane)
- Pelvic pain
- Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
- Vulvovaginal candidiasis (vulvovaginal infection by fungi)
- Weight decreased
- Coma (state of unconsciousness lasting more than six hours)
- Myoclonic jerks (involuntary twitching of a muscle or group of muscles)
30-39:
- Chest pain
- Diarrhoea
- Nausea (feeling of having an urge to vomit)
- Renal failure acute (rapid kidney dysfunction)
- Blood creatinine increased
- Blood potassium increased
- Bone pain
- Fatigue (feeling of tiredness)
- Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
- Vomiting
40-49:
- Escherichia bacteraemia (presence of bacteria escherichia coli in the blood)
- Fatigue (feeling of tiredness)
- Gait disturbance
- Haematocrit decreased
- Haemoglobin decreased
- Hepatic failure (liver failure)
- Herpes simplex (herpes simplex is a common viral infection)
- Herpes virus infection
- Hypochloraemia (electrolyte disturbance in which there is an abnormally low level of the chloride ion in the blood)
- Limb discomfort (discomfort in leg)
50-59:
- Bone density decreased
- Cerebral haemorrhage (bleeding within the brain)
- Emotional distress
- Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
- Erysipelas (bacterial skin infection)
- Fear of falling
- Haemoglobin decreased
- Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
- Nephrolithiasis (calculi in the kidneys)
- Optic neuropathy (optic nerve damage)
60+:
- Anaemia (lack of blood)
- Depression
- Dizziness
- Renal failure acute (rapid kidney dysfunction)
- Lung infection pseudomonal (bacterial infection of lung by pseudomonas aeruginosa)
- Multi-organ failure (multisystem organ failure)
What are the existing conditions these people have? *
- Depression: 8 people, 8.16%
- Kaposi's Sarcoma (a tumour caused by human herpes virus): 5 people, 5.10%
* Approximation only. Some reports may have incomplete information.
Do you take Norvir and Neupogen?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Norvir and Neupogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Norvir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Neupogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Norvir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neupogen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ritonavir and filgrastim (the active ingredients of Norvir and Neupogen, respectively), and Norvir and Neupogen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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