Novalgin and Pemetrexed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Novalgin (metamizole) and Pemetrexed (pemetrexed). Common drug interactions include sepsis among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Novalgin and Pemetrexed. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.

What is Pemetrexed?

Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.

On Jul, 14, 2026

74 people who take Novalgin and Pemetrexed together, and have interactions are studied.

Novalgin and Pemetrexed drug interactions.

What are the common drug interactions of Novalgin and Pemetrexed, by gender? *:

female:

Sepsis (a severe blood infection that can lead to organ failure and death)
Sleep disorder
Stomatitis (inflammation of mucous membrane of mouth)
Hypertension (high blood pressure)
General physical health deterioration (weak health status)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Device related infection
Dyspnoea exertional (breathlessness or shortness of breath)
Epistaxis (bleed from the nose)
Haematoma (collection of blood outside the blood vessels)

male:

Pneumonia
Mucosal inflammation (infection of mucous membrane)
Gastritis (inflammation of stomach)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Metastases to central nervous system (cancer spreads to central nervous system)
Vasculitis (inflammation of a blood vessel or blood vessels)
Vomiting

What are the common drug interactions of Novalgin and Pemetrexed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pyrexia (fever)
Vomiting

50-59:

White blood cell count decreased
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Device related infection
Dyspnoea exertional (breathlessness or shortness of breath)
Epistaxis (bleed from the nose)
General physical health deterioration (weak health status)
Haematoma (collection of blood outside the blood vessels)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Weight decreased
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

60+:

Mucosal inflammation (infection of mucous membrane)
Dysphagia (a condition in which swallowing is difficult or painful)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
General physical health deterioration (weak health status)
Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
Dehydration (dryness resulting from the removal of water)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neutropenia (an abnormally low number of neutrophils)
Vasculitis (inflammation of a blood vessel or blood vessels)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 45 people, 60.81%
High Blood Pressure: 33 people, 44.59%
Nausea (feeling of having an urge to vomit): 20 people, 27.03%
Constipation: 14 people, 18.92%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 9 people, 12.16%
Anaemia (lack of blood): 8 people, 10.81%
Depression: 8 people, 10.81%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 8 people, 10.81%
Insomnia (sleeplessness): 8 people, 10.81%
Tumor Pain: 7 people, 9.46%

* Approximation only. Some reports may have incomplete information.

Do you take Novalgin and Pemetrexed?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously