Novalgin and Votrient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Novalgin (metamizole) and Votrient (pazopanib hydrochloride). Common drug interactions include general physical health deterioration among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Novalgin and Votrient. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Novalgin?

Novalgin has active ingredients of metamizole. It is often used in pain. eHealthMe is studying from 10,177 Novalgin users. Check the latest studies of Novalgin.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 25,347 Votrient users. Check the latest studies of Votrient.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

53 people who take Novalgin and Votrient together, and have interactions are studied.

Novalgin and Votrient drug interactions.

What are the common drug interactions of Novalgin and Votrient, by gender? *:

female:

General physical health deterioration (weak health status)
Hypertension (high blood pressure)
Leiomyosarcoma (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue)
Liver disorder (liver diseases)
Metastases to lymph nodes (cancer spreads to lymph node)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Oral candidiasis (fungal infection of mouth)
Paresis (a condition of muscular weakness)

male:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Aspartate aminotransferase increased
Hallucination (an experience involving the perception of something not present)
Pyrexia (fever)
Fatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)
Malignant neoplasm progression (cancer tumour came back)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Chest discomfort

What are the common drug interactions of Novalgin and Votrient, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Nausea (feeling of having an urge to vomit)
C-reactive protein increased
Blood potassium decreased
Blood potassium increased
Blood thyroid stimulating hormone increased
Chills (felling of cold)
Cholecystitis acute (rapid infection of gallbladder)
Conjunctival oedema (conjunctival swelling)
Decreased appetite
Dysgeusia (disorder of the sense of taste)

What are the existing conditions these people have? *

High Blood Pressure: 26 people, 49.06%
Back Pain: 18 people, 33.96%
Type 2 Diabetes: 14 people, 26.42%
Nausea (feeling of having an urge to vomit): 10 people, 18.87%
Urinary Tract Infection: 9 people, 16.98%
Constipation: 9 people, 16.98%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 9 people, 16.98%
Depression: 9 people, 16.98%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 15.09%
High Blood Cholesterol: 7 people, 13.21%

* Approximation only. Some reports may have incomplete information.

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