Novolog and Ascorbate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Novolog (insulin aspart recombinant) and Ascorbate (vitamin c (ascorbic acid)). Common drug interactions include cognitive disorder among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Novolog and Ascorbate. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Novolog?

Novolog has active ingredients of insulin aspart recombinant. It is often used in diabetes. eHealthMe is studying from 56,160 Novolog users. Check the latest studies of Novolog.

What is Ascorbate?

Ascorbate has active ingredients of vitamin c (ascorbic acid). eHealthMe is studying from 1,446 Ascorbate users. Check the latest studies of Ascorbate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 20, 2026

15 people who take Novolog and Ascorbate together, and have interactions are studied.

Novolog and Ascorbate drug interactions.

What are the common drug interactions of Novolog and Ascorbate, by gender? *:

female:

  1. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  2. Chronic kidney disease
  3. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  4. Depression
  5. Dry skin
  6. Eye pruritus (eye itching)
  7. Fall
  8. Infection
  9. Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash)
  10. Mobility decreased (ability to move is reduced)

male:

  1. Death

What are the common drug interactions of Novolog and Ascorbate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anxiety
  2. Depression
  3. Eye pruritus (eye itching)
  4. Pain of skin
  5. Pruritus (severe itching of the skin)
  6. Skin ulcer

40-49:

n/a

50-59:

  1. Acute myocardial infarction (acute heart attack)
  2. Chronic kidney disease
  3. Dry skin
  4. Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash)
  5. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  6. Neurodermatitis (a skin disorder characterized by long lasting itching and scratching)
  7. Pruritus (severe itching of the skin)
  8. Renal failure (kidney dysfunction)
  9. Skin burning sensation

60+:

  1. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  2. Femur fracture
  3. Mobility decreased (ability to move is reduced)
  4. Muscle contractions involuntary (uncontrolled muscle contraction)
  5. Oropharyngeal pain
  6. Weight decreased
  7. Chronic kidney disease
  8. Diarrhoea
  9. Renal failure (kidney dysfunction)
  10. Renal tubular necrosis (death of kidney tubules)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 33.33%
  2. Neurodermatitis (a skin disorder characterized by long lasting itching and scratching): 4 people, 26.67%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 13.33%
  4. Pain: 2 people, 13.33%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 13.33%
  6. High Blood Cholesterol: 2 people, 13.33%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
  8. Drowsiness: 2 people, 13.33%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 13.33%
  10. Pulmonary Vascular Disorder: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Novolog and Ascorbate?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Novolog and Ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Novolog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ascorbate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Novolog and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ascorbate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on insulin aspart recombinant and vitamin c (ascorbic acid) (the active ingredients of Novolog and Ascorbate, respectively), and Novolog and Ascorbate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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