Novolog and Provera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Novolog (insulin aspart recombinant) and Provera (medroxyprogesterone acetate). Common drug interactions include dyspnoea among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Novolog and Provera. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Novolog?

Novolog has active ingredients of insulin aspart recombinant. It is often used in diabetes. eHealthMe is studying from 56,160 Novolog users. Check the latest studies of Novolog.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

On Jul, 28, 2026

77 people who take Novolog and Provera together, and have interactions are studied.

What are the common drug interactions of Novolog and Provera, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Wound
Cerebral thrombosis (blood clot in brain)
Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)
Nausea (feeling of having an urge to vomit)
Vomiting
Somnolence (a state of near-sleep, a strong desire for sleep)
Agitation (state of anxiety or nervous excitement)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pulmonary embolism (blockage of the main artery of the lung)

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
General physical health deterioration (weak health status)
Injury
Pain
Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Novolog and Provera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cerebral thrombosis (blood clot in brain)
Superior sagittal sinus thrombosis (blood clot in the dural venous sinuses, which drain blood from the brain)
Transverse sinus thrombosis (a blood clot in transverse sinus)
Obesity (having too much body fat)

20-29:

Dyspnoea (difficult or laboured respiration)
Chest discomfort
Completed suicide (act of taking one's own life)
Confusional state
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Depression
Enuresis (repeated inability to control urination)
Insomnia (sleeplessness)
Lung transplant rejection (failure of lung transplant)

30-39:

Pulmonary embolism (blockage of the main artery of the lung)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporotic fracture (fracture due to weak bone)
Abasia (inability to walk)
Abdominal pain
Anaemia (lack of blood)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood creatinine increased
Blood pressure increased
Chest pain

40-49:

Abdominal pain upper
Abscess limb (limb infection)
Activities of daily living impaired
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Agitation (state of anxiety or nervous excitement)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Anxiety

50-59:

Dyspnoea (difficult or laboured respiration)
Balance disorder
Sluggishness (lacking alertness)
Somnolence (a state of near-sleep, a strong desire for sleep)
Anxiety
Breast cancer female
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Loss of consciousness

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Device related infection
Alopecia (absence of hair from areas of the body)
Anger
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Mood swings (an extreme or rapid change in mood)
Suicidal ideation
Asthenia (weakness)
Blood glucose increased
Blood sodium decreased

What are the existing conditions these people have? *

Pain: 12 people, 15.58%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 15.58%
Depression: 12 people, 15.58%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 10.39%
Cardiac Disorder: 8 people, 10.39%
High Blood Cholesterol: 6 people, 7.79%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.79%
Blood Pressure Abnormal: 6 people, 7.79%
Stress And Anxiety: 5 people, 6.49%
Sleep Disorder: 4 people, 5.19%

* Approximation only. Some reports may have incomplete information.

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