Noxafil and Clonidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Noxafil (posaconazole) and Clonidine (clonidine). Common drug interactions include klebsiella infection among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Noxafil and Clonidine. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Noxafil?

Noxafil has active ingredients of posaconazole. eHealthMe is studying from 5,919 Noxafil users. Check the latest studies of Noxafil.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.



On Jul, 10, 2026

33 people who take Noxafil and Clonidine together, and have interactions are studied.

Noxafil and Clonidine drug interactions.

What are the common drug interactions of Noxafil and Clonidine, by gender? *:

female:

  1. Klebsiella infection
  2. Migraine (headache)
  3. Petechiae (a small red or purple spot caused by bleeding into the skin)
  4. Skin atrophy (wasting of skin)
  5. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  6. Upper respiratory tract infection
  7. Weight decreased
  8. Vomiting
  9. Nausea (feeling of having an urge to vomit)
  10. Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)

male:

  1. Abdominal distension
  2. Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
  3. Cough
  4. Cushingoid (obesity and weakening of the muscles)
  5. Decreased appetite
  6. Dyspnoea (difficult or laboured respiration)
  7. Encephalopathy (functioning of the brain is affected by some agent or condition)
  8. Epistaxis (bleed from the nose)
  9. Facial paralysis (loss of function of face muscle)
  10. Febrile neutropenia (fever with reduced white blood cells)

What are the common drug interactions of Noxafil and Clonidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal distension
  2. Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
  3. Aspergillus test positive
  4. Bacteraemia (presence of bacteria in the blood)
  5. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  6. C-reactive protein increased
  7. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  8. Cerebral atrophy (decrement in size of brain)
  9. Cerebral ventricle dilatation (enlargement of ventricle of brain)
  10. Confusional state

20-29:

  1. Abdominal pain upper
  2. Drug ineffective
  3. Dyspnoea (difficult or laboured respiration)
  4. Hospitalisation
  5. Nausea (feeling of having an urge to vomit)
  6. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  7. Vomiting
  8. Weight decreased

30-39:

n/a

40-49:

n/a

50-59:

  1. Influenza
  2. Skin lesion
  3. Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
  4. Arthralgia (joint pain)
  5. B precursor type acute leukaemia (lymphoid cancer)
  6. Diarrhoea
  7. Dyspnoea (difficult or laboured respiration)
  8. Fluid overload (too much fluid in the blood)
  9. Fluid retention (an abnormal accumulation of fluid in the blood)
  10. Generalised oedema (swelling all over the body)

60+:

  1. Abdominal distension
  2. Nephrolithiasis (calculi in the kidneys)
  3. Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
  4. Petechiae (a small red or purple spot caused by bleeding into the skin)
  5. Pulmonary mycosis (lung infection caused by yeast-like fungi)
  6. Scrotal oedema (swelling of scrotum)
  7. Skin atrophy (wasting of skin)
  8. Pain in extremity
  9. Gout (uric acid crystals building up in the body)
  10. Bacterial test positive

What are the existing conditions these people have? *

  1. Cystic Fibrosis (disease of the secretary glands): 9 people, 27.27%
  2. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 21.21%
  3. Acute Lymphocytic Leukaemia Recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 4 people, 12.12%
  4. Infection: 2 people, 6.06%
  5. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 6.06%
  6. B Precursor Type Acute Leukaemia (lymphoid cancer): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Noxafil and Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Noxafil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Noxafil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on posaconazole and clonidine (the active ingredients of Noxafil and Clonidine, respectively), and Noxafil and Clonidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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