Nplate and Amoxicillin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nplate (romiplostim) and Amoxicillin (amoxicillin). Common drug interactions include intervertebral disc degeneration among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Nplate and Amoxicillin. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.

On Jul, 13, 2026

47 people who take Nplate and Amoxicillin together, and have interactions are studied.

Nplate and Amoxicillin drug interactions.

What are the common drug interactions of Nplate and Amoxicillin, by gender? *:

female:

Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Lethargy (tiredness)
Localised oedema (fluid retention in a particular part of the body)
Metastases to bone (cancer spreads to bone)
Metastases to pelvis (cancer spreads to pelvis)
Metastases to spine (cancer spreads to spine)
Myalgia (muscle pain)
Neuropathy peripheral (surface nerve damage)
Onychomycosis (fungal infection of the nail)

male:

Thrombocytopenia (decrease of platelets in blood)
Lymphoma (cancer that begins in immune system cells)
Enterocolitis infectious
Fatigue (feeling of tiredness)
Hypokalaemia (low potassium)
Influenza like illness
Leukocytosis (increased white blood cells)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pseudohyperkalaemia (marked increase of in vitro serum potassium levels)
Purpura (purplish discoloration of the skin)

What are the common drug interactions of Nplate and Amoxicillin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pneumonia
Thrombocytopenia (decrease of platelets in blood)
Wound secretion
Drug ineffective
Lymphoma (cancer that begins in immune system cells)
Splenomegaly (enlargement of spleen)
Therapeutic response decreased (less preventive response)
Arthralgia (joint pain)
Back pain
Blood triglycerides increased

20-29:

Pain in extremity

30-39:

n/a

40-49:

Blood glucose decreased
Erythema (redness of the skin)
Fatigue (feeling of tiredness)
Feeling hot
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Injection site pain
Lethargy (tiredness)
Myalgia (muscle pain)
Pain

50-59:

Marrow hyperplasia (increased bone marrow)
Neutropenia (an abnormally low number of neutrophils)
Abdominal pain
Acute respiratory failure
Asthenia (weakness)
Bone marrow reticulin fibrosis (thickening and scarring of bone marrow reticulin)
Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
Coagulopathy (blood's ability to clot is impaired)
Drug hypersensitivity
Insomnia (sleeplessness)

60+:

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Anaemia (lack of blood)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pseudohyperkalaemia (marked increase of in vitro serum potassium levels)
Purpura (purplish discoloration of the skin)
Septic shock (shock due to blood infection)
Thrombocytopenia (decrease of platelets in blood)
Urinary hesitation (difficulty in beginning the flow of urine)
Urinary tract obstruction
Volvulus (obstruction caused by twisting of the stomach or intestine)

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 29 people, 61.70%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 10 people, 21.28%
Anaemia (lack of blood): 6 people, 12.77%

* Approximation only. Some reports may have incomplete information.

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