Nucala and Effexor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nucala (mepolizumab) and Effexor (venlafaxine hydrochloride). Common drug interactions include eosinophilia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Nucala and Effexor. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Nucala?

Nucala has active ingredients of mepolizumab. eHealthMe is studying from 26,883 Nucala users. Check the latest studies of Nucala.

What is Effexor?

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. eHealthMe is studying from 99,493 Effexor users. Check the latest studies of Effexor.

On Jul, 12, 2026

27 people who take Nucala and Effexor together, and have interactions are studied.

What are the common drug interactions of Nucala and Effexor, by gender? *:

female:

Eosinophilia (eosinophil count in the peripheral blood exceeds)
Renal impairment (severely reduced kidney function)
Respiratory tract inflammation
Secretion discharge
Arthralgia (joint pain)
Drug hypersensitivity
Dyspnoea exertional (breathlessness or shortness of breath)
Eosinophil count increased
Forced expiratory volume increased (increased lung expired air volume)
Joint injury

male:

Arthralgia (joint pain)
Injection site pain
Muscle disorder (muscle disease)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Pain in extremity

What are the common drug interactions of Nucala and Effexor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Conjunctivitis (pink eye)
Dry eye (lack of adequate tears)
Ocular rosacea (redness, irritation or burning of the eyes)

40-49:

Arthralgia (joint pain)
Areflexia (absence of a reflex)
Asthma
Drug hypersensitivity
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Eosinophil count increased
Forced expiratory volume increased (increased lung expired air volume)
Joint injury
Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)

50-59:

Hallucination (an experience involving the perception of something not present)
Injection site pruritus (severe itching at injection site)
Injection site rash

60+:

Asthma
Cough
Balance disorder
Contusion (a type of hematoma of tissue in which capillaries)
Fall
Injection site erythema (redness at injection site)
Oedema peripheral (superficial swelling)
Pruritus (severe itching of the skin)
Rash
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)

What are the existing conditions these people have? *

Asthma: 19 people, 70.37%
Stress And Anxiety: 2 people, 7.41%
Immunodeficiency Common Variable: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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