Nuedexta and Folic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuedexta (dextromethorphan hydrobromide; quinidine sulfate) and Folic acid (folic acid). Common drug interactions include headache among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Nuedexta and Folic acid. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Nuedexta?

Nuedexta has active ingredients of dextromethorphan hydrobromide; quinidine sulfate. eHealthMe is studying from 3,781 Nuedexta users. Check the latest studies of Nuedexta.

What is Folic acid?

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,027 Folic acid users. Check the latest studies of Folic acid.



On Aug, 10, 2026

13 people who take Nuedexta and Folic acid together, and have interactions are studied.

Nuedexta and Folic acid drug interactions.

What are the common drug interactions of Nuedexta and Folic Acid, by gender? *:

female:

  1. Headache (pain in head)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  4. Vomiting
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Dizziness
  7. Fall
  8. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  9. Infusion site oedema (swelling from excessive accumulation of watery fluid from infusion site)
  10. Limb injury

male:

  1. Anxiety
  2. Asthenia (weakness)
  3. Renal failure (kidney dysfunction)
  4. Screaming (a long loud piercing cry)
  5. Therapeutic response unexpected
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Vision blurred
  8. Crying
  9. Depression
  10. Gait disturbance

What are the common drug interactions of Nuedexta and Folic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Dizziness
  2. Euphoric mood (excessively happy but may become angry or irritable)
  3. Headache (pain in head)

40-49:

n/a

50-59:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Urinary tract infection

60+:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  3. Heart rate decreased
  4. Hypotension (abnormally low blood pressure)
  5. Insomnia (sleeplessness)
  6. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  7. Renal disorder (kidney disease)
  8. Renal failure (kidney dysfunction)
  9. Screaming (a long loud piercing cry)
  10. Surgery

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 38.46%
  2. Affect Lability (emotional incontinence): 3 people, 23.08%
  3. Immunodeficiency Common Variable: 2 people, 15.38%
  4. Depression: 2 people, 15.38%
  5. Blood Folate Decreased: 1 person, 7.69%
  6. Cough: 1 person, 7.69%
  7. Dementia (madness): 1 person, 7.69%
  8. Diabetes: 1 person, 7.69%
  9. Dizziness: 1 person, 7.69%
  10. Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nuedexta and Folic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nuedexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Folic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuedexta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Folic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dextromethorphan hydrobromide; quinidine sulfate and folic acid (the active ingredients of Nuedexta and Folic acid, respectively), and Nuedexta and Folic acid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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