Nuedexta and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nuedexta (dextromethorphan hydrobromide; quinidine sulfate) and Premarin (estrogens, conjugated). Common drug interactions include cognitive disorder among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Nuedexta and Premarin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Nuedexta?

Nuedexta has active ingredients of dextromethorphan hydrobromide; quinidine sulfate. eHealthMe is studying from 3,781 Nuedexta users. Check the latest studies of Nuedexta.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 10, 2026

13 people who take Nuedexta and Premarin together, and have interactions are studied.

Nuedexta and Premarin drug interactions.

What are the common drug interactions of Nuedexta and Premarin, by gender? *:

female:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Dizziness
Fall
Fatigue (feeling of tiredness)
Functional gastrointestinal disorder (functional problem in separate organs of gastrointestinal system)
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Mobility decreased (ability to move is reduced)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

male:

Drug ineffective
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Somnambulism (sleep walking)
Suicidal ideation
Suicide attempt

What are the common drug interactions of Nuedexta and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease

50-59:

Complex partial seizures (epileptic seizure)

60+:

Flatulence (flatus expelled through the anus)
Nausea (feeling of having an urge to vomit)
Alopecia (absence of hair from areas of the body)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 53.85%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 23.08%
High Blood Cholesterol: 2 people, 15.38%
Stress And Anxiety: 1 person, 7.69%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 7.69%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.69%
Cardiac Disorder: 1 person, 7.69%
Crying: 1 person, 7.69%
Depression: 1 person, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Nuedexta and Premarin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously