Nulytely and Doxycycline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nulytely (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride) and Doxycycline (doxycycline hyclate). Common drug interactions include chronic kidney disease among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Nulytely and Doxycycline. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Nulytely?

Nulytely has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride. eHealthMe is studying from 1,377 Nulytely users. Check the latest studies of Nulytely.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 60,868 Doxycycline users. Check the latest studies of Doxycycline.



On Aug, 05, 2026

19 people who take Nulytely and Doxycycline together, and have interactions are studied.

Nulytely and Doxycycline drug interactions.

What are the common drug interactions of Nulytely and Doxycycline, by gender? *:

female:

  1. Chronic kidney disease
  2. Arteriosclerosis (thickening and hardening of arteries)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Atypical femur fracture
  5. Comminuted fracture (bone has broken into several pieces)
  6. Drug intolerance (drug sensitivity)
  7. Fall
  8. Femur fracture
  9. Foot fracture
  10. Fracture nonunion (permanent failure of healing following a broken bone)

male:

  1. Arthralgia (joint pain)
  2. Pain
  3. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  4. Dyspepsia (indigestion)
  5. Fatigue (feeling of tiredness)
  6. Fear, focus
  7. Gastric erosions (gradual destruction of surface layer of the membrane lining the stomach)
  8. Gastroenteritis helicobacter (inflammation of stomach and intestine caused by helicobacter infection)
  9. Influenza
  10. Testicular pain (pain in testes)

What are the common drug interactions of Nulytely and Doxycycline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  3. Cough
  4. Pain
  5. Pyrexia (fever)
  6. Rhinitis allergic (inflammation of the nasal airways due to allergy)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anxiety
  9. Cardiac disorder
  10. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

50-59:

  1. Burning sensation
  2. Chronic kidney disease
  3. Cystitis (inflammation of the wall of the bladder)
  4. Erythema (redness of the skin)
  5. Frostbite (damage is caused to skin and other tissues due to freezing)
  6. Gastroenteritis (inflammation of stomach and intestine)
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Joint range of motion decreased (disease of joint movement)
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Pain

60+:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Fall
  4. Femur fracture
  5. Foot fracture
  6. Fracture nonunion (permanent failure of healing following a broken bone)
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Open fracture
  9. Pathological fracture (broken bone caused by disease)
  10. Pneumonia

What are the existing conditions these people have? *

  1. Nausea (feeling of having an urge to vomit): 5 people, 26.32%
  2. Pain: 5 people, 26.32%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 21.05%
  4. Migraine (headache): 3 people, 15.79%
  5. Asthma: 3 people, 15.79%
  6. Infection: 3 people, 15.79%
  7. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 15.79%
  8. Oral Fungal Infection: 3 people, 15.79%
  9. Diarrhea: 3 people, 15.79%
  10. Headache (pain in head): 3 people, 15.79%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Nulytely and Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nulytely:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Doxycycline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nulytely and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Doxycycline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride and doxycycline hyclate (the active ingredients of Nulytely and Doxycycline, respectively), and Nulytely and Doxycycline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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