Nulytely and Valproate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nulytely (polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride) and Valproate sodium (valproate sodium). Common drug interactions include burning sensation among females and antipsychotic drug level increased among males.

The phase IV clinical study analyzes what interactions people have when they take Nulytely and Valproate sodium. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Nulytely?

Nulytely has active ingredients of polyethylene glycol 3350; potassium chloride; sodium bicarbonate; sodium chloride. eHealthMe is studying from 1,377 Nulytely users. Check the latest studies of Nulytely.

What is Valproate sodium?

Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.

On Jul, 28, 2026

24 people who take Nulytely and Valproate sodium together, and have interactions are studied.

Nulytely and Valproate sodium drug interactions.

What are the common drug interactions of Nulytely and Valproate Sodium, by gender? *:

female:

Burning sensation
Blood osmolarity decreased
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Blood sodium decreased
Cardiac failure congestive
Chest pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Injury
Localised infection (infection at the single location)
Mucosal inflammation (infection of mucous membrane)

male:

Antipsychotic drug level increased
Blood sodium increased
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Drug abuse
Agitation (state of anxiety or nervous excitement)
Asthenia (weakness)
Athetosis (a condition in which abnormal muscle contractions cause involuntary writhing movements)
Chorea (abnormal involuntary movement disorder)
Depressed mood
Multiple myeloma (cancer of the plasma cells)

What are the common drug interactions of Nulytely and Valproate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Agitation (state of anxiety or nervous excitement)
Athetosis (a condition in which abnormal muscle contractions cause involuntary writhing movements)
Chorea (abnormal involuntary movement disorder)
Depressed mood
Oropharyngeal pain
Suicidal behaviour
Pancreatitis (inflammation of pancreas)
Renal failure acute (rapid kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)

20-29:

Anxiety
Heart rate increased
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

30-39:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Obesity (having too much body fat)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Syncope (loss of consciousness with an inability to maintain postural tone)
Weight increased

40-49:

n/a

50-59:

Burning sensation
Blood osmolarity decreased
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Blood sodium decreased
Asthenia (weakness)
Multiple myeloma (cancer of the plasma cells)
Spinal compression fracture (fracture due to spinal compression on bone)
Injury
Localised infection (infection at the single location)
Mucosal inflammation (infection of mucous membrane)

60+:

Antipsychotic drug level increased
Drug abuse
Cardiac failure congestive
Chest pain
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)
Rash morbilliform (a rash that looks like measles)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 7 people, 29.17%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 7 people, 29.17%
Pain: 7 people, 29.17%
Joint Swelling: 6 people, 25.00%
Depression: 6 people, 25.00%
Constipation: 6 people, 25.00%
Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 4 people, 16.67%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 3 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.50%
Sleep Disorder: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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