Nystop and Xyrem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Nystop (nystatin) and Xyrem (sodium oxybate). Common drug interactions include hypothyroidism among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Nystop and Xyrem. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Nystop?

Nystop has active ingredients of nystatin. eHealthMe is studying from 1,310 Nystop users. Check the latest studies of Nystop.

What is Xyrem?

Xyrem has active ingredients of sodium oxybate. It is often used in narcolepsy. eHealthMe is studying from 81,487 Xyrem users. Check the latest studies of Xyrem.

On Jul, 10, 2026

57 people who take Nystop and Xyrem together, and have interactions are studied.

What are the common drug interactions of Nystop and Xyrem, by gender? *:

female:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Infertility
Intestinal haemorrhage (bleeding from intestine)
Joint injury
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Intervertebral disc protrusion (spinal disc protrusion)
Iron deficiency anaemia
Vitamin d deficiency
Concussion (short loss of normal brain function in response to a head injury)

male:

Drug ineffective
Hepatic enzyme increased
Disability
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug hypersensitivity
Fibromyalgia (a long-term condition which causes pain all over the body)
Finger deformity (a deformed position of the finger)
Foot deformity (functional disability of foot)
Hypersensitivity
Hypokinesia (decreased bodily movement)

What are the common drug interactions of Nystop and Xyrem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Emotional disorder
Nasopharyngitis (inflammation of the nasopharynx)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Panic attack
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicidal ideation

30-39:

Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Gait disturbance
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Infertility

40-49:

Anaemia (lack of blood)
Bipolar disorder (mood disorder)
Blood pressure decreased
Headache (pain in head)
Self-injurious ideation
Suicidal ideation
Therapeutic response unexpected

50-59:

Blood potassium decreased
Dehydration (dryness resulting from the removal of water)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

60+:

Balance disorder
Bruxism (habitual grinding of the teeth, typically during sleep)
Tooth extraction
Tooth infection
Toothache (tooth pain)
Abdominal injury
Back disorder
Dementia (madness)
Dental caries
Drug ineffective

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 37 people, 64.91%
Drowsiness: 20 people, 35.09%
Allergic Sinusitis: 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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