Ocrevus and Gralise drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ocrevus (ocrelizumab) and Gralise (gabapentin). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Ocrevus and Gralise. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Ocrevus?

Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.

What is Gralise?

Gralise has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 4,282 Gralise users. Check the latest studies of Gralise.

On Jul, 22, 2026

12 people who take Ocrevus and Gralise together, and have interactions are studied.

What are the common drug interactions of Ocrevus and Gralise, by gender? *:

female:

Fatigue (feeling of tiredness)
Herpes zoster
Pain
Abdominal distension
Abdominal pain upper
Arthralgia (joint pain)
Drug ineffective
Lhermitte's sign (an electrical sensation that runs down the back and into the limbs)
Micturition disorder (disease of passing urine)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)

male:

n/a

What are the common drug interactions of Ocrevus and Gralise, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Fatigue (feeling of tiredness)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Abdominal distension
Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)
Asthenia (weakness)
Drug ineffective
Headache (pain in head)
Lhermitte's sign (an electrical sensation that runs down the back and into the limbs)

50-59:

Pain
Throat irritation
Urinary tract infection

60+:

Herpes zoster
Intervertebral disc protrusion (spinal disc protrusion)
Blood glucose increased
Depression
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Tooth loss
Vitreous floaters (spots before the eyes)

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 50.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 33.33%
Muscle Spasms (muscle contraction): 3 people, 25.00%
Depression: 3 people, 25.00%
Pain: 3 people, 25.00%
Stress And Anxiety: 2 people, 16.67%
Diabetes: 2 people, 16.67%
High Blood Pressure: 2 people, 16.67%
Insomnia (sleeplessness): 2 people, 16.67%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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