Ofev and Gemfibrozil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ofev (nintedanib esylate) and Gemfibrozil (gemfibrozil). Common drug interactions include diarrhoea among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Ofev and Gemfibrozil. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Ofev?

Ofev has active ingredients of nintedanib esylate. eHealthMe is studying from 24,791 Ofev users. Check the latest studies of Ofev.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

20 people who take Ofev and Gemfibrozil together, and have interactions are studied.

What are the common drug interactions of Ofev and Gemfibrozil, by gender? *:

female:

Diarrhoea
Cough
Viral infection
Nausea (feeling of having an urge to vomit)
Epistaxis (bleed from the nose)
Arthropathy
Dehydration (dryness resulting from the removal of water)
Respiratory tract infection
Upper respiratory tract infection
Vomiting

male:

Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Diarrhoea
Epistaxis (bleed from the nose)
Fall
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Heart rate increased
Heart rate irregular
Jaw fracture
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the common drug interactions of Ofev and Gemfibrozil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Chest discomfort
Constipation
Cough
Fall
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Heart rate increased
Heart rate irregular
Jaw fracture

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 9 people, 45.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 35.00%
Type 2 Diabetes: 2 people, 10.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 10.00%
Stress And Anxiety: 2 people, 10.00%
High Blood Pressure: 2 people, 10.00%
Gout (uric acid crystals building up in the body): 2 people, 10.00%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 2 people, 10.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 10.00%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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