Olanzapine and Reglan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Olanzapine (olanzapine) and Reglan (metoclopramide hydrochloride). Common drug interactions include dry mouth among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Olanzapine and Reglan. It is created by eHealthMe based on reports of 72 people who take the same drugs from the FDA, and is updated regularly.
What is Olanzapine?
Olanzapine has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 69,242 Olanzapine users. Check the latest studies of Olanzapine.
What is Reglan?
Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.
72 people who take Olanzapine and Reglan together, and have interactions are studied.

What are the common drug interactions of Olanzapine and Reglan, by gender? *:
female:
- Dry mouth
- Hypertension (high blood pressure)
- Obesity (having too much body fat)
- Weight decreased
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
- Bile duct cancer
- Biliary dilatation
- Bladder dysfunction
- Breast cancer metastatic
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
male:
- Dyspnoea (difficult or laboured respiration)
- Infection
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Haemorrhage intracranial (bleeding within the skull)
- Oxygen saturation decreased
- Pain
- Splenic necrosis (death of most or all of the cells of spleen)
- Splenic vein thrombosis (blood clot in splenic vein)
- Acute respiratory failure
- Headache (pain in head)
What are the common drug interactions of Olanzapine and Reglan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Vomiting
- Acne (skin problems that cause pimples)
- Acute respiratory distress syndrome
- Anaemia (lack of blood)
- Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Diarrhoea
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
30-39:
- Abdominal pain
- Decreased appetite
- Failure to thrive (inadequate weight gain and physical growth in children)
- Hydronephrosis (water inside the kidney)
- Pelvic mass
- Vomiting
- Abdominal pain upper
- Brain injury
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
40-49:
- Headache (pain in head)
- Hypertension (high blood pressure)
- Nervousness
- Nightmare (unpleasant dream)
- Obesity (having too much body fat)
- Pain
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Photosensitivity reaction
- Restlessness (not able to rest)
- Strabismus (a disorder in which the two eyes do not line up in the same direction)
50-59:
- Diarrhoea
- Febrile neutropenia (fever with reduced white blood cells)
- Mucosal inflammation (infection of mucous membrane)
- Tardive dyskinesia (a disorder that involves involuntary movements)
- Acute respiratory failure
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Contusion (a type of hematoma of tissue in which capillaries)
- Crying
- Disturbance in attention
60+:
- Aortic thrombosis (formation of a blood clot inside aorta)
- Cerebral thrombosis (blood clot in brain)
- Oxygen saturation decreased
- Splenic necrosis (death of most or all of the cells of spleen)
- Splenic vein thrombosis (blood clot in splenic vein)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Pain
- Restless legs syndrome (a powerful urge to move your legs)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Vomiting
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 13 people, 18.06%
- Pain: 10 people, 13.89%
- Nausea And Vomiting: 9 people, 12.50%
- Stress And Anxiety: 8 people, 11.11%
- Immunodeficiency Common Variable: 7 people, 9.72%
- Diarrhea: 7 people, 9.72%
- Depression: 7 people, 9.72%
- Breast Cancer Metastatic: 6 people, 8.33%
- Insomnia (sleeplessness): 5 people, 6.94%
- Constipation: 5 people, 6.94%
* Approximation only. Some reports may have incomplete information.
Do you take Olanzapine and Reglan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Olanzapine (69,242 reports)
- Reglan (29,455 reports)
Browse all drug interactions of Olanzapine and Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Olanzapine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Olanzapine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Reglan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
- Gupta SK, Shwetank B, "Reversible bilateral sensori-neural hearing loss due to olanzapine in a male suffering from bipolar affective disorder", Indian journal of pharmacology, 2014 Jan .
- Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on olanzapine and metoclopramide hydrochloride (the active ingredients of Olanzapine and Reglan, respectively), and Olanzapine and Reglan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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